Neuronal remodeling is a conserved mechanism that eliminates unwanted neurites and can
include the loss of cell bodies. In these processes, a key role for glial cells in events from …

How does the brain translate sensory information into complex behaviors? With relatively
small neuronal numbers, readable behavioral outputs, and an unparalleled genetic toolkit …

Gene editing by CRISPR/Cas9 is commonly used to generate germline mutations or perform
in vitro screens, but applicability for in vivo screening has so far been limited. Recently, it …

Individual neurons can undergo drastic structural changes, known as neuronal remodeling
or structural plasticity. One example of this is in response to hormones, such as during …

As animals mature from embryonic to adult stages, the skin grows and acquires specialized
appendages, like hairs, feathers, and scales. How cutaneous blood vessels and sensory …

Developmental neuronal remodeling is an evolutionarily conserved mechanism required for
precise wiring of nervous systems. Despite its fundamental role in neurodevelopment and …

Steroid hormones control various aspects of brain development and behavior in metazoans,
but how they enter the central nervous system (CNS) through the blood-brain barrier (BBB) …

Many organisms enter a dormant state in their life cycle to deal with predictable changes in
environments over the course of a year. The timing of dormancy is therefore a key seasonal …

Many cell types display the remarkable ability to alter their cellular phenotype in response to
specific external or internal signals. Such phenotypic plasticity is apparent in the nematode …

Behavioral plasticity is key to animal survival. Harpegnathos saltator ants can switch
between worker and queen-like status (gamergate) depending on the outcome of social …