Diabetic retinopathy: a comprehensive update on in vivo, in vitro and ex vivo experimental models

MZ Sadikan, NA Abdul Nasir, L Lambuk… - BMC …, 2023 - Springer
Diabetic retinopathy (DR), one of the leading causes of visual impairment and blindness
worldwide, is one of the major microvascular complications in diabetes mellitus (DM) …

Diabetic retinopathy: emerging concepts of current and potential therapy

MZ Sadikan, NA Abdul Nasir - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
Diabetic retinopathy (DR) is one of the leading causes of permanent central blindness
worldwide. Despite the complexity and inadequate understanding of DR pathogenesis …

Tocotrienol-rich fraction reduces retinal inflammation and angiogenesis in rats with streptozotocin-induced diabetes

MZ Sadikan, NA Abdul Nasir, NS Bakar… - … Medicine and Therapies, 2023 - Springer
Background Diabetic retinopathy (DR) is the second commonest microvascular complication
of diabetes mellitus. It is characterized by chronic inflammation and angiogenesis. Palm oil …

Molecular Mechanisms of Vitamin E in Ocular Neurodegenerative Disorders: An Update on the Emerging Evidence and Therapeutic Implications

MZ Sadikan, L Lambuk, N Reshidan… - Journal of Ocular …, 2025 - liebertpub.com
Vitamin E is renowned for its potent antioxidant properties, crucial for shielding cells against
oxidative stress and damage. Deficiency in this vitamin can lead to various health issues …

Tocotrienol-rich fraction (TRF) protects against retinal cell apoptosis and preserves visual behavior in rats with streptozotocin-induced diabetic retinopathy

Y Goh, MZ Sadikan, H Jaiprakash, NAA Nasir… - … Medicine and Therapies, 2024 - Springer
Background Tocotrienol is a vitamin E analogue that is known to exert anti-inflammatory and
antioxidant effects. Hence, in the current study, the effects of TRF on the expression of pro …

[HTML][HTML] Identifying the stability of housekeeping genes to be used for the quantitative real-time PCR normalization in retinal tissue of streptozotocin-induced diabetic …

MZ Sadikan, NAA Nasir, MJ Ibahim… - International Journal …, 2024 - ncbi.nlm.nih.gov
AIM To investigate the stability of the seven housekeeping genes: beta-actin (ActB),
glyceraldehyde-3-phosphate dehydrogenase (GAPDH), 18s ribosomal unit 5 (18s) …

The Role of Natural Products in Diabetic Retinopathy

Y Zhao, Y Chen, N Yan - Biomedicines, 2024 - mdpi.com
Diabetic retinopathy (DR) is one of the most severe complications of diabetes mellitus and
potentially leads to significant visual impairment and blindness. The complex mechanisms …

[PDF][PDF] Oil palm economic performance in Malaysia and R&D progress in 2023

GKA PARVEEZ, SSEN LEOW… - Journal of Oil Palm …, 2024 - researchgate.net
Malaysia is the second largest palm oil producer in the world. This review article highlights
the performance of the industry in 2023 and the recent R&D progress throughout the entire …