Chromones are a group of naturally occurring compounds that are ubiquitous in nature,
especially in plants. The word chromone is derived from the Greek word chroma, meaning …

Chroman-4-one scaffold is a privileged structure in heterocyclic chemistry and drug
discovery. Also, chroman-4-ones are important intermediates and interesting building blocks …

The inhibitory action of fifteen benzyloxy ortho/para-substituted chalcones (B1-B15) was
evaluated against human monoamine oxidases (hMAOs). All the molecules inhibited hMAO …

Structural information of butyrylcholinesterase (BChE) and its variants associated with
several diseases are discussed here. Pure human BChE has been proved safe and effective …

Monoamine oxidase is a flavin enzyme that catalyzes the oxidation of monoamine
neurotransmitters in the brain. Various toxic by-products, aldehydes and hydrogen peroxide …

Monoamine oxidase (MAO) inhibitors have made significant contributions and remain an
indispensable approach of molecular and mechanistic diversity for the discovery of …

Chromones are the class of secondary metabolites that broadly occur in the plant kingdom
in a noticeable quantity. This rigid bicyclic system has been categorized “as privileged …

This is an overview of the metabolic reactions of drugs, natural products, physiological
compounds, and other (general) chemicals catalyzed by flavin monooxygenase (FMO) …

Monoamine oxidases (MAOs) are a family of flavin adenine dinucleotide-dependent
enzymes that catalyze the oxidative deamination of a wide range of endogenous and …

Neuropsychiatric disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD)
and depression, have seriously inconvenienced the lives of patients. Growing evidence …