Virus detection: from state‐of‐the‐art laboratories to smartphone‐based point‐of‐care testing

M Xiao, F Tian, X Liu, Q Zhou, J Pan, Z Luo… - Advanced …, 2022 - Wiley Online Library
Infectious virus outbreaks pose a significant challenge to public healthcare systems. Early
and accurate virus diagnosis is critical to prevent the spread of the virus, especially when no …

Microfluidics-based strategies for molecular diagnostics of infectious diseases

X Wang, XZ Hong, YW Li, Y Li, J Wang, P Chen… - Military Medical …, 2022 - Springer
Traditional diagnostic strategies for infectious disease detection require benchtop
instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a …

Microfluidic space coding for multiplexed nucleic acid detection via CRISPR-Cas12a and recombinase polymerase amplification

Z Xu, D Chen, T Li, J Yan, J Zhu, T He, R Hu… - Nature …, 2022 - nature.com
Fast, inexpensive, and multiplexed detection of multiple nucleic acids is of great importance
to human health, yet it still represents a significant challenge. Herein, we propose a nucleic …

On-site airborne pathogen detection for infection risk mitigation

G Qiu, X Zhang, AJ deMello, M Yao, J Cao… - Chemical Society …, 2023 - pubs.rsc.org
Human-infecting pathogens that transmit through the air pose a significant threat to public
health. As a prominent instance, the severe acute respiratory syndrome coronavirus 2 …

Recent progress in microfluidic biosensors with different driving forces

Y Liu, H Shen, X Yang, S Kang, L Cai, T Tian… - TrAC Trends in …, 2023 - Elsevier
Microfluidic biosensors integrating fluid control, target recognition, as well as signal
transduction and output, have been widely used in the field of disease diagnosis, drug …

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

H Yuan, P Chen, C Wan, Y Li, BF Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Abstract The Coronavirus disease 2019 (COVID-19) outbreak has urged the establishment
of a global-wide rapid diagnostic system. Current widely-used tests for COVID-19 include …

Ceria-based nanozymes in point-of-care diagnosis: an emerging futuristic approach for biosensing

R Wang, Y Du, Y Fu, Y Guo, X Gao, X Guo, J Wei… - ACS …, 2023 - ACS Publications
In recent years, there has been a notable increase in interest surrounding nanozymes due to
their ability to imitate the functions and address the limitations of natural enzymes. The …

Toward rapid and accurate molecular diagnostics at home

W Liu, LP Lee - Advanced Materials, 2023 - Wiley Online Library
The global outbreaks of infectious diseases have significantly driven an imperative demand
for rapid and accurate molecular diagnostics. Nucleic acid amplification tests (NAATs) …

On-Line Dual-Active Valves Based Centrifugal Microfluidic Chip for Fully Automated Point-of-Care Immunoassay

C Qian, C Wan, S Li, Y Xiao, H Yuan, S Gao… - Analytical …, 2023 - ACS Publications
There remains an unmet need for a fully integrated microfluidic platform that can
automatically perform multistep and multireagent immunoassays. Here, we proposed a …

Integrated microfluidic devices for in vitro diagnostics at point of care

D Liu, Y Wang, X Li, M Li, Q Wu, Y Song, Z Zhu… - …, 2022 - Wiley Online Library
Given the continuous and growing demand for point of care (POC) diagnostic tests, attention
has been shifted toward integration and miniaturization of laboratory protocols into “sample …