The ADAMs family of transmembrane proteins belongs to the zinc protease superfamily.
Members of the family have a modular design, characterized by the presence of …

An ADAM is a transmembrane protein that contains a disintegrin and metalloprotease
domain and, therefore, it potentially has both cell adhesion and protease activities …

The elastic fibre system has a principal role in the structure and function of various types of
organs that require elasticity, such as large arteries, lung and skin,. Although elastic fibres …

ADAMs are proteins containing a disintegrin and metalloproteinase domain. Several
important insights were provided in the past year regarding ADAM metalloproteinases …

Metalloprotease-disintegrins (ADAMs) have captured our attention as key players in
fertilization and in the processing of the ectodomains of proteins such as tumor necrosis …

The ADAMs (a disintegrin and metalloproteinase) comprise a family of multidomain
transmembrane and secreted proteins. One of their best-established roles is the release of …

Atherosclerosis develops and progresses at the arterial wall mediated by interactions
between numerous growth factors, cytokines and vasoregulatory molecules that regulate …

A disintegrin and metalloproteinases (ADAMs) are a recently discovered family of proteins
that share the metalloproteinase domain with matrix metalloproteinases (MMPs). Among this …

Pancreatic ductal adenocarcinoma (PDAC) has a grim prognosis with< 5% survivors after 5
years. High expression levels of ADAM8, a metalloprotease disintegrin, are correlated with …

The ADAMs (a disintegrin and metalloprotease) family of proteins is involved in a variety of
cellular interactions, including cell adhesion and ecto-domain shedding. Here we show that …