Considerations for polymers used in ocular drug delivery

MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …

Recent advances of intraocular lens materials and surface modification in cataract surgery

C Luo, H Wang, X Chen, J Xu, H Yin… - … in Bioengineering and …, 2022 - frontiersin.org
Advances in cataract surgery have increased the demand for intraocular lens (IOL)
materials. At present, the progress of IOL materials mainly contains further improving …

Electrospun PGS/PCL, PLLA/PCL, PLGA/PCL and pure PCL scaffolds for retinal progenitor cell cultivation

S Behtaj, F Karamali, E Masaeli, YG Anissimov… - Biochemical …, 2021 - Elsevier
Recent advances in cell transplantation technologies have shown that polymeric fibrous
tissue-engineered scaffolds provide a suitable physical environment, including the structural …

Therapeutic approaches for age-related macular degeneration

RM Galindo-Camacho, C Blanco-Llamero… - International journal of …, 2022 - mdpi.com
Damage to the retinal pigment epithelium, Bruch's membrane and/or tissues underlying
macula is known to increase the risk of age-related macular degeneration (AMD). AMD is …

Retinal cell transplantation, biomaterials, and in vitro models for developing next-generation therapies of age-related macular degeneration

LJ Rizzolo, IO Nasonkin… - Stem Cells Translational …, 2022 - academic.oup.com
Retinal pigment epithelium (RPE) cells grown on a scaffold, an RPE patch, have potential to
ameliorate visual impairment in a limited number of retinal degenerative conditions. This …

Pharmaceutical, biomedical and ophthalmic applications of biodegradable polymers (BDPs): literature and patent review

B Osi, M Khoder, AA Al-Kinani… - Pharmaceutical …, 2022 - Taylor & Francis
In the last few decades, the interest in biodegradable materials for biomedical applications
has increased significantly. Both natural and synthetic biodegradable polymers (BDPs) have …

Long-acting formulation strategies for protein and peptide delivery in the treatment of PSED

A Garkal, P Bangar, A Rajput, P Pingale, N Dhas… - Journal of Controlled …, 2022 - Elsevier
The invigoration of protein and peptides in serious eye disease includes age-related
macular degeneration, choroidal neovascularization, retinal neovascularization, and …

Injectable hydrogel based on gellan gum/silk sericin for application as a retinal pigment epithelium cell carrier

S Kim, GY Jeon, SE Kim, SH Choe, SJ Kim, JS Seo… - ACS …, 2022 - ACS Publications
The damage to retinal pigment epithelium (RPE) cells can lead to vision loss and permanent
blindness. Therefore, an effective therapeutic strategy has emerged to replace damaged …

Recent trends in drug delivery and emerging biomedical applications of gelatin for ophthalmic indications

D Rana, S Salave, G Rawat, D Benival - Macromolecular Research, 2022 - Springer
Gelatin serves as a versatile carrier system for delivering therapeutically active agents to the
ocular surface owing to its inherent attributes like biocompatibility, biodegradability, targeting …

Polymeric materials for eye surface and intraocular applications

M Karayilan, L Clamen, ML Becker - Biomacromolecules, 2021 - ACS Publications
Ocular applications of polymeric materials have been widely investigated for medical
diagnostics, treatment, and vision improvement. The human eye is a vital organ that …