Methods for time‐varying exposure related problems in pharmacoepidemiology: an overview

L Pazzagli, M Linder, M Zhang, E Vago… - … and drug safety, 2018 - Wiley Online Library
Purpose Lack of control for time‐varying exposures can lead to substantial bias in estimates
of treatment effects. The aim of this study is to provide an overview and guidance on some of …

[HTML][HTML] What we mean when we talk about adherence in respiratory medicine

B Vrijens, AL Dima, E Van Ganse… - The Journal of Allergy …, 2016 - Elsevier
Adequate medication adherence is key for optimal benefit of pharmacological treatments. A
wealth of research has been conducted to understand and identify opportunities to intervene …

Considerations for pharmacoepidemiological studies of drug–cancer associations

A Pottegård, S Friis, T Stürmer, J Hallas… - Basic & clinical …, 2018 - Wiley Online Library
In this MiniReview, we provide general considerations for the planning and conduct of
pharmacoepidemiological studies of associations between drug use and cancer …

Risk of major bleeding among users of direct oral anticoagulants combined with interacting drugs: a population‐based nested case–control study

Y Zhang, PC Souverein, H Gardarsdottir… - British journal of …, 2020 - Wiley Online Library
Aims To assess the association between concurrent use of potential pharmacokinetic or
pharmacodynamic interacting drugs and major bleeding among direct oral anticoagulant …

[HTML][HTML] Computation of adherence to medication and visualization of medication histories in R with AdhereR: Towards transparent and reproducible use of electronic …

AL Dima, D Dediu - PloS one, 2017 - journals.plos.org
Adherence to medications is an important indicator of the quality of medication management
and impacts on health outcomes and cost-effectiveness of healthcare delivery. Electronic …

Incidence of direct oral anticoagulant use in patients with nonvalvular atrial fibrillation and characteristics of users in 6 European countries (2008–2015): A cross …

L Ibáñez, M Sabaté, X Vidal, E Ballarin… - British Journal of …, 2019 - Wiley Online Library
Aims To estimate the incidence of direct oral anticoagulant drug (DOAC) use in patients with
nonvalvular atrial fibrillation and to describe user and treatment characteristics in 8 …

Use of sodium-glucose cotransporter-2 inhibitors and the risk for sudden cardiac arrest and for all-cause death in patients with type 2 diabetes mellitus

TE Eroglu, R Coronel, CJ Zuurbier… - European Heart …, 2023 - academic.oup.com
Aims Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) are antidiabetic agents that can
have direct cardiac effects by impacting on cardiac ion transport mechanisms that control …

Adherence to prophylaxis and bleeding outcome in haemophilia: a multicentre study

LSH Schrijvers… - British Journal of …, 2016 - Wiley Online Library
Prevention of bleeding and joint damage in severe haemophilia is dependent on adherence
to prophylactic replacement therapy. The aim of this study was to assess adherence to …

Assigning exposure duration to single prescriptions by use of the waiting time distribution

A Pottegård, J Hallas - Pharmacoepidemiology and drug safety, 2013 - Wiley Online Library
Purpose The purpose of this study is to develop and present a method to calculate which
exposure duration should be assigned to single prescriptions for use in databases where …

[HTML][HTML] Understanding statin non-adherence: knowing which perceptions and experiences matter to different patients

H Wouters, L Van Dijk, HCJ Geers, NA Winters… - PloS one, 2016 - journals.plos.org
Background Non-adherence to statins is substantial and is associated with numerous
perceptions and experiences. However, time limits in clinical practice constrain in depth …