[HTML][HTML] Models for cytotoxicity screening of antileishmanial drugs: what has been done so far?

MBC Brioschi, EM Coser, AC Coelho… - International Journal of …, 2022 - Elsevier
A growing number of studies have demonstrated the in vitro potential of an impressive
number of antileishmanial candidates in the past years. However, the lack of uniformity …

The dichapetalins and dichapetalin-type compounds: structural diversity, bioactivity, and future research perspectives

I Addae-Mensah, GA Dziwornu, MA Chama… - Natural Product …, 2024 - pubs.rsc.org
Covering mainly from 2013 up to 2023 with relevant references to work done before
2013First reported in 1995, the dichapetalins and analogous compounds constitute a novel …

Antimicrobial and in silico studies of the triterpenoids of Dichapetalum albidum

MA Chama, GA Dziwornu, E Popli, E Mas-Claret… - Heliyon, 2023 - cell.com
Here we report a new polyhydroxylated triterpene, 2β, 6β, 21α-trihydroxyfriedelan-3-one (4)
isolated from the root and stem bark of Dichapetalum albidum A. Chev (Dichapetalaceae) …

Dichapetalins from the Twigs of Dichapetalum longipetalum with Cytotoxic Activities

B Zhou, XH Gao, MM Zhang, HC Liu… - Journal of Natural …, 2022 - ACS Publications
Continued efforts to expand the structural diversity of dichapetalins and explore further the
cytotoxic structure–activity relationships have led to the isolation of 17 undescribed …

Evaluation of the Antitrypanosomal Activity of the Crude Extracts of Uvaria Ovata: In vitro and In silico Approach

MA Chama, B Egyir, KBA Owusu… - Biomedical and …, 2024 - journals.lww.com
Background: Human African trypanosomiasis is the third disease with most mortalities
among the neglected tropical diseases. The absence of vaccines and the development of …