Radioactive main group and rare earth metals for imaging and therapy

TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Gallium-based liquid metal particles for therapeutics

W Xie, FM Allioux, JZ Ou, E Miyako, SY Tang… - Trends in …, 2021 - cell.com
Gallium (Ga) and Ga-based liquid metal (LM) alloys offer low toxicity, excellent electrical and
thermal conductivities, and fluidity at or near room temperature. Ga-based LM particles …

[HTML][HTML] Gallium and gallium compounds: New insights into the “Trojan horse” strategy in medical applications

W Sun, M Qi, S Cheng, C Li, B Dong, L Wang - Materials & Design, 2023 - Elsevier
Infection, inflammation, tumors, and other illnesses have for a long time posed a major
danger to human health and have developed into a global public health issue. However, the …

Recent advances in radiometals for combined imaging and therapy in cancer

N Herrero Álvarez, D Bauer, J Hernández‐Gil… - …, 2021 - Wiley Online Library
Nuclear medicine is defined as the use of radionuclides for diagnostic and therapeutic
applications. The imaging modalities positron emission tomography (PET) and single …

Radionuclides for targeted therapy: physical properties

C Stokke, M Kvassheim, J Blakkisrud - Molecules, 2022 - mdpi.com
A search in PubMed revealed that 72 radionuclides have been considered for molecular or
functional targeted radionuclide therapy. As radionuclide therapies increase in number and …

The chemical scaffold of theranostic radiopharmaceuticals: radionuclide, bifunctional chelator, and pharmacokinetics modifying linker

HA Holik, FM Ibrahim, AA Elaine, BD Putra, A Achmad… - Molecules, 2022 - mdpi.com
Therapeutic radiopharmaceuticals have been researched extensively in the last decade as
a result of the growing research interest in personalized medicine to improve diagnostic …

68Ga-THP-PSMA: a PET imaging agent for prostate cancer offering rapid, room-temperature, 1-step kit-based radiolabeling

JD Young, V Abbate, C Imberti… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The clinical impact and accessibility of 68Ga tracers for the prostate-specific membrane
antigen (PSMA) and other targets would be greatly enhanced by the availability of a simple …

Mucin-1 conjugated polyamidoamine-based nanoparticles for image-guided delivery of gefitinib to breast cancer

PN Nabi, N Vahidfar, MR Tohidkia, AA Hamidi… - International journal of …, 2021 - Elsevier
PAMAM dendrimers (PAMs) are a group of polymeric macromolecules with distinctive
physicochemical features, which can make them multifunctional theranostic nanoparticles …

EANM position paper on the role of radiobiology in nuclear medicine

A Aerts, U Eberlein, S Holm, R Hustinx… - European journal of …, 2021 - Springer
With an increasing variety of radiopharmaceuticals for diagnostic or therapeutic nuclear
medicine as valuable diagnostic or treatment option, radiobiology plays an important role in …

[HTML][HTML] Perspectives on metals-based radioimmunotherapy (RIT): moving forward

JM White, FE Escorcia, NT Viola - Theranostics, 2021 - ncbi.nlm.nih.gov
Radioimmunotherapy (RIT) is FDA-approved for the clinical management of liquid
malignancies, however, its use for solid malignancies remains a challenge. The putative …