In the last two decades, multi (MDR), extensively (XDR), extremely (XXDR) and total (TDR)
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …

Tuberculosis (TB) remains one of the deadliest infectious diseases in the world and every 20
seconds a person dies from TB. An important attribute of human TB is induction of a …

Granulomas are the pathological hallmark of tuberculosis (TB) and the niche where bacilli
can grow and disseminate or the immunological microenvironment in which host cells …

The diagnosis of pleural tuberculosis (TB) is problematic. The comparative performance of
newer same-day tools for pleural TB, including Xpert MTB/RIF Ultra (ULTRA), has hitherto …

Rationale: A human model to better understand tuberculosis immunopathogenesis and
facilitate vaccine development is urgently needed. Objectives: We evaluated the feasibility …

Disequilibrium of CD4+ T-cell subpopulations in peripheral blood (PB) of patients with
primary immune thrombocytopenia (ITP) has been well established, whereas the profile of …

Tuberculosis (TB) is one of the top 10 causes of mortality worldwide from a single infectious
agent and has significant implications for global health. A major hurdle in the development …

Protective immunity against Mycobacterium tuberculosis is poorly understood. The role of
interleukin (IL)-4, the archetypal T-helper type 2 (Th2) cytokine, in the immunopathogenesis …

Many subversive mechanisms promote the occurrence and development of chronic
infectious diseases and cancer, among which the down-regulated expression of immune …

Background Tuberculosis (TB) is an infectious disease. During TB, regulatory T cells (Treg)
are related to poor prognosis. However, information about conventional and unconventional …