Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Interactions of fungal pathogens with phagocytes

LP Erwig, NAR Gow - Nature Reviews Microbiology, 2016 - nature.com
The surveillance and elimination of fungal pathogens rely heavily on the sentinel behaviour
of phagocytic cells of the innate immune system, especially macrophages and neutrophils …

Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation

L López-Maury, S Marguerat, J Bähler - Nature Reviews Genetics, 2008 - nature.com
Organisms are constantly exposed to a wide range of environmental changes, including
both short-term changes during their lifetime and longer-term changes across generations …

Candida albicans Cell Wall Proteins

WLJ Chaffin - Microbiology and molecular biology reviews, 2008 - Am Soc Microbiol
The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans

A da Silva Dantas, A Day, M Ikeh, I Kos, B Achan… - Biomolecules, 2015 - mdpi.com
Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …

Oxidative stress response pathways in fungi

H Yaakoub, S Mina, A Calenda, JP Bouchara… - Cellular and Molecular …, 2022 - Springer
Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …

Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs

RT Todd, A Selmecki - Elife, 2020 - elifesciences.org
Previously, we identified long repeat sequences that are frequently associated with genome
rearrangements, including copy number variation (CNV), in many diverse isolates of the …

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

IV Ene, AK Adya, S Wehmeier, AC Brand… - Cellular …, 2012 - Wiley Online Library
The survival of all microbes depends upon their ability to respond to environmental
challenges. To establish infection, pathogens such as C andida albicans must mount …

Redox control and oxidative stress in yeast cells

E Herrero, J Ros, G Bellí, E Cabiscol - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
Protein structure and function can be altered by reactive oxygen species produced either by
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …