Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
B Walter, S Hirsch, L Kuhlburger, A Stahl… - Journal of Experimental …, 2024 - Springer
Background The DNA damage response (DDR) is a physiological network preventing
malignant transformation, eg by halting cell cycle progression upon DNA damage detection …
malignant transformation, eg by halting cell cycle progression upon DNA damage detection …
To explore the prognostic characteristics of colon cancer based on tertiary lymphoid structure-related genes and reveal the characteristics of tumor microenvironment …
Z Wang, D Niu - Scientific Reports, 2024 - nature.com
In order to construct a prognostic evaluation model of TLS features in COAD and better
realize personalized precision medicine in COAD. Colon adenocarcinoma (COAD) is a …
realize personalized precision medicine in COAD. Colon adenocarcinoma (COAD) is a …
The ATR inhibitor berzosertib acts as a radio-and chemosensitizer in head and neck squamous cell carcinoma cell lines
J Schnoell, C Sparr, S Al-Gboore, M Haas… - Investigational New …, 2023 - Springer
Alterations in the DNA damage response play a crucial role in radio-and chemoresistance of
neoplastic cells. Activation of the Ataxia telangiectasia and Rad3-related (ATR) pathway is …
neoplastic cells. Activation of the Ataxia telangiectasia and Rad3-related (ATR) pathway is …