Alternatives to conventional antibiotics in the era of antimicrobial resistance

C Ghosh, P Sarkar, R Issa, J Haldar - Trends in microbiology, 2019 - cell.com
As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted
towards alternative therapies for treating infections. Although several alternatives already …

Structure–activity relationship of cationic surfactants as antimicrobial agents

C Zhou, Y Wang - Current Opinion in Colloid & Interface Science, 2020 - Elsevier
Cationic surfactants are widely used as antimicrobial agents in various fields. However, the
widespread use of cationic surfactants has caused huge accumulation in environment …

Peptidomimetic polyurethanes inhibit bacterial biofilm formation and disrupt surface established biofilms

A Vishwakarma, F Dang, A Ferrell… - Journal of the …, 2021 - ACS Publications
Over 80% of all chronic bacterial infections in humans are associated with biofilms, which
are surface-associated bacterial communities encased within a secreted exopolysaccharide …

Recent progress in polymer research to tackle infections and antimicrobial resistance

MM Konai, B Bhattacharjee, S Ghosh… - …, 2018 - ACS Publications
Global health is increasingly being threatened by the rapid emergence of drug-resistant
microbes. The ability of these microbes to form biofilms has further exacerbated the scenario …

Photo-responsive chitosan/Ag/MoS2 for rapid bacteria-killing

M Zhu, X Liu, L Tan, Z Cui, Y Liang, Z Li… - Journal of hazardous …, 2020 - Elsevier
Bacterial infection is a serious problem threatening human health. The chitosan (CS)-
modified MoS 2 coating loaded with silver nanoparticles (Ag NPs) was designed on the …

Synergy by perturbing the gram-negative outer membrane: opening the door for gram-positive specific antibiotics

CMJ Wesseling, NI Martin - ACS Infectious Diseases, 2022 - ACS Publications
New approaches to target antibacterial agents toward Gram-negative bacteria are key, given
the rise of antibiotic resistance. Since the discovery of polymyxin B nonapeptide as a potent …

Dual corona vesicles with intrinsic antibacterial and enhanced antibiotic delivery capabilities for effective treatment of biofilm-induced periodontitis

Y Xi, Y Wang, J Gao, Y Xiao, J Du - ACS nano, 2019 - ACS Publications
Periodontitis is a common disease caused by plaque biofilms, which are important
pathogenic factors of many diseases and may be eradicated by antibiotic therapy. However …

A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics

P Sarkar, V Yarlagadda, C Ghosh, J Haldar - Medchemcomm, 2017 - pubs.rsc.org
Cell wall biosynthesis inhibitors (CBIs) have historically been one of the most effective
classes of antibiotics. They are the most extensively used class of antibiotics and their …

Biodegradable cationic and ionizable cationic lipids: A roadmap for safer pharmaceutical excipients

AM Jörgensen, R Wibel, A Bernkop‐Schnürch - Small, 2023 - Wiley Online Library
Cationic and ionizable cationic lipids are broadly applied as auxiliary agents, but their use is
associated with adverse effects. If these excipients are rapidly degraded to endogenously …

High Antibacterial Activity of Functionalized Chemically Exfoliated MoS2

S Pandit, S Karunakaran, SK Boda… - ACS applied materials …, 2016 - ACS Publications
In view of the implications of inherent resistance of pathogenic bacteria, especially ESKAPE
pathogens toward most of the commercially available antibiotics and the importance of these …