Anticancer activity of natural coumarins for biological targets

A Önder - Studies in natural products chemistry, 2020 - Elsevier
Coumarins are a class of secondary metabolites and naturally occurring benzopyrone
derivatives. Previously, the identification of natural coumarins from natural sources has been …

Synthetic and naturally occurring heterocyclic anticancer compounds with multiple biological targets

RK Amewu, PO Sakyi, D Osei-Safo, I Addae-Mensah - Molecules, 2021 - mdpi.com
Cancer is a complex group of diseases initiated by abnormal cell division with the potential
of spreading to other parts of the body. The advancement in the discoveries of omics and bio …

Chitosan-encapsulated nickel oxide, tin dioxide, and farnesol nanoparticles: antimicrobial and anticancer properties in breast cancer cells

S Mickymaray, MS Al Aboody, MM Eraqi… - International Journal of …, 2023 - Elsevier
Breast cancer is the most frequent cancer in women; however, it is curable in most cases (up
to 80%) when detected and treated at an early non-metastatic stage. Nanotechnology has …

Effects of quercetin-loaded nanoparticles on MCF-7 human breast cancer cells

F Niazvand, M Orazizadeh, L Khorsandi, M Abbaspour… - Medicina, 2019 - mdpi.com
Background and objectives: Previous studies have shown anti-tumor activity of quercetin
(QT). However, the low bioavailability of QT has restricted its use. This study aimed to assess …

Manufacturing drug co-loaded liposomal formulations targeting breast cancer: Influence of preparative method on liposomes characteristics and in vitro toxicity

L Gkionis, RA Campbell, H Aojula, LK Harris… - International journal of …, 2020 - Elsevier
Developing more efficient manufacturing methods for nano therapeutic systems is becoming
important, not only to better control their physico-chemical characteristics and therapeutic …

New amino acid Schiff bases as anticancer agents via potential mitochondrial complex I-associated hexokinase inhibition and targeting AMP-protein kinases/mTOR …

AA Noser, AH Abdelmonsef, M El-Naggar, MM Salem - Molecules, 2021 - mdpi.com
Two series of novel amino acid Schiff base ligands containing heterocyclic moieties, such as
quinazolinone 3–11 and indole 12–20 were successfully synthesized and confirmed by …

Preparation and characterization of the farnesiferol C-loaded solid lipid nanoparticles decorated with folic acid-bound chitosan and evaluation of its in vitro anti-cancer …

MH Tabrizi, M Soltani, A Es-haghi - Journal of Molecular Liquids, 2023 - Elsevier
Farnesiferol C (FC) has long been used as a cancer prevention agent. In the present study,
FC was loaded into solid lipid nanoparticles (SLN) coated with folic acid (FA) bound …

RETRACTED: Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells …

HM Aldawsari, OAA Ahmed, NA Alhakamy… - Pharmaceutics, 2021 - mdpi.com
Raloxifene hydrochloride (RLX), an antiosteoporotic agent, has been utilized for guarding
against breast cancer and recently, for the disease management owing to its estrogen …

Vascular endothelial growth factor receptors [VEGFR] as target in breast cancer treatment: current status in preclinical and clinical studies and future directions

M Malekan, MA Ebrahimzadeh - Current Topics in Medicinal …, 2022 - ingentaconnect.com
Breast cancer [BC] is one of the most common cancers among women, one of the leading
causes of a considerable number of cancer-related death globally. Among all procedures …

Poly-(lactic-co-glycolic) acid nanoparticles for synergistic delivery of epirubicin and paclitaxel to human lung cancer cells

N Sharma, RM Kumari, N Gupta, A Syed, AH Bahkali… - Molecules, 2020 - mdpi.com
Combination therapy using chemically distinct drugs has appeared as one of the promising
strategies to improve anticancer treatment efficiency. In the present investigation, poly-(lactic …