Challenging the ischemic core concept in acute ischemic stroke imaging

M Goyal, JM Ospel, B Menon, M Almekhlafi… - Stroke, 2020 - Am Heart Assoc
Endovascular treatment is a highly effective therapy for acute ischemic stroke due to large
vessel occlusion and has recently revolutionized stroke care. Oftentimes, ischemic core …

Review of perfusion imaging in acute ischemic stroke: from time to tissue

J Demeestere, A Wouters, S Christensen, R Lemmens… - Stroke, 2020 - Am Heart Assoc
Background Occlusion of a cerebral blood vessel causes a variable decrease of blood flow
in the downstream parenchyma proportionate to the degree of collateral circulation. In brain …

Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a …

BCV Campbell, CBLM Majoie, GW Albers… - The Lancet …, 2019 - thelancet.com
Background CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection
for endovascular thrombectomy. We aimed to establish whether imaging assessments of …

Artificial intelligence for decision support in acute stroke—current roles and potential

A Bivard, L Churilov, M Parsons - Nature Reviews Neurology, 2020 - nature.com
The identification and treatment of patients with stroke is becoming increasingly complex as
more treatment options become available and new relationships between disease features …

Comparison of three commonly used CT perfusion software packages in patients with acute ischemic stroke

MS Koopman, OA Berkhemer… - Journal of …, 2019 - jnis.bmj.com
Background and purpose CT perfusion (CTP) might support decision making in patients with
acute ischemic stroke by providing perfusion maps of ischemic tissue. Currently, the …

Assessment of computed tomography perfusion software in predicting spatial location and volume of infarct in acute ischemic stroke patients: a comparison of Sphere …

RA Rava, KV Snyder, M Mokin, M Waqas… - Journal of …, 2021 - jnis.bmj.com
Background CT perfusion (CTP) infarct and penumbra estimations determine the eligibility of
patients with acute ischemic stroke (AIS) for endovascular intervention. This study aimed to …

Accuracy of CT perfusion–based core estimation of follow-up infarction: effects of time since last known well

A Sarraj, BCV Campbell, S Christensen, CW Sitton… - Neurology, 2022 - AAN Enterprises
Background and Objectives To assess the accuracy of baseline CT perfusion (CTP)
ischemic core estimates. Methods From SELECT (Optimizing Patient Selection for …

Association of Mismatch Profiles and Clinical Outcome from Endovascular Therapy in Large Infarct: A Post‐Hoc Analysis of the ANGEL‐ASPECT Trial

X Huo, TN Nguyen, D Sun, Raynald, Y Pan… - Annals of …, 2024 - Wiley Online Library
Objectives We investigated whether patients with large infarct and the presence or absence
of perfusion mismatch are associated with endovascular treatment benefit. Methods This is a …

Improvement of automatic ischemic stroke lesion segmentation in CT perfusion maps using a learned deep neural network

M Soltanpour, R Greiner, P Boulanger… - Computers in biology and …, 2021 - Elsevier
Acute ischemic stroke is one of the leading causes of death and long-term disability
worldwide. It occurs when a blood clot blocks an artery that supplies blood to the brain …

Comparison of automated CT perfusion softwares in evaluation of acute ischemic stroke

Y Xiong, CC Huang, M Fisher, DB Hackney… - Journal of Stroke and …, 2019 - Elsevier
Abstract Background and Purpose: Automated imaging software is integral to decision-
making in acute ischemic stroke (AIS) during extended time windows. RAPID software is the …