Highlights•Phosphoproteomic technologies deliver highly informative data to aide drug
discovery.•Technologies include mass spectrometry and suspension and planar protein …

Although advances in psychotherapy have been made in recent years, drug discovery for
brain diseases such as schizophrenia and mood disorders has stagnated. The need for new …

Cross-referencing experimental data with our current knowledge of signaling network
topologies is one central goal of mathematical modeling of cellular signal transduction …

Objective Chondrocyte signaling is widely identified as a key component in cartilage
homeostasis. Dysregulations of the signaling processes in chondrocytes often result in …

We introduce the caspo toolbox, a python package implementing a workflow for reasoning
on logical networks families. Our software allows researchers to (i) learn a family of logical …

Modeling of signal transduction pathways plays a major role in understanding cells' function
and predicting cellular response. Mathematical formalisms based on a logic formalism are …

This study aimed to investigate whether single nucleotide polymorphisms (SNPs) located
near the gene of the ABO blood group play an important role in the genetic aetiology of …

Logic models of signaling pathways are a promising way of building effective in silico
functional models of a cell, in particular of signaling pathways. The automated learning of …

A variety of pathway/gene-set approaches have been proposed to provide evidence of
higher-level biological phenomena in the association of expression with experimental …

Chronic inflammation is associated with the development of human hepatocellular
carcinoma (HCC), an essentially incurable cancer. Anti‐inflammatory nutraceuticals have …