Machine learning in precision diabetes care and cardiovascular risk prediction

EK Oikonomou, R Khera - Cardiovascular Diabetology, 2023 - Springer
Artificial intelligence and machine learning are driving a paradigm shift in medicine,
promising data-driven, personalized solutions for managing diabetes and the excess …

Cardiovascular care innovation through data-driven discoveries in the electronic health record

LS Dhingra, M Shen, A Mangla, R Khera - The American Journal of …, 2023 - Elsevier
The electronic health record (EHR) represents a rich source of patient information,
increasingly being leveraged for cardiovascular research. Although its primary use remains …

Underuse of GLP-1 receptor agonists in the management of type 2 diabetes despite a favorable benefit-safety profile

AJ Scheen - Expert Opinion on Drug Safety, 2024 - Taylor & Francis
Introduction Patients with type 2 diabetes (T2DM) are at high risk of atherosclerotic
cardiovascular disease (ASCVD) and cardiovascular death. Cardiovascular protection is a …

Development and multinational validation of an algorithmic strategy for high Lp(a) screening

A Aminorroaya, LS Dhingra, EK Oikonomou… - Nature Cardiovascular …, 2024 - nature.com
Abstract Elevated lipoprotein (a)(Lp (a)) is associated with premature atherosclerotic
cardiovascular disease. However, fewer than 0.5% of individuals undergo Lp (a) testing …

Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice: JACC State-of-the-Art Review

R Khera, EK Oikonomou, GN Nadkarni… - Journal of the American …, 2024 - jacc.org
Artificial intelligence (AI) has the potential to transform every facet of cardiovascular practice
and research. The exponential rise in technology powered by AI is defining new frontiers in …

[HTML][HTML] Paradoxical real-life underuse of GLP-1 receptor agonists in type 2 diabetes patients with atherosclerotic cardiovascular disease: Underuse of GLP-1RAs in …

AJ Scheen - Diabetes Epidemiology and Management, 2024 - Elsevier
Introduction Glucagon-like peptide-1 receptor agonists (GLP-1RAs) reduce the risk of
cardiovascular (CV) complications in patients with type 2 diabetes (T2DM) and …

[HTML][HTML] Designing medical artificial intelligence systems for global use: focus on interoperability, scalability, and accessibility

EK Oikonomou, R Khera - Hellenic Journal of Cardiology, 2024 - Elsevier
Advances in artificial intelligence (AI) and machine learning systems promise faster, more
efficient and more personalized care. While many of these models are built on the premise …

Artificial intelligence-enhanced patient evaluation: bridging art and science

EK Oikonomou, R Khera - European Heart Journal, 2024 - academic.oup.com
The advent of digital health and artificial intelligence (AI) has promised to revolutionize
clinical care, but real-world patient evaluation has yet to witness transformative changes. As …

Lifting the Veil on Advanced Heart Failure

AT Sandhu, R Khera - Heart Failure, 2023 - jacc.org
Despite remarkable advances in the treatment of heart failure (HF), for some, this
progressive condition continues to worsen over time. Among the 6 million US adults with HF …

[HTML][HTML] Comparative Effectiveness of Second-line Antihyperglycemic Agents for Cardiovascular Outcomes: A Large-scale, Multinational, Federated Analysis of the …

R Khera, A Aminorroaya, LS Dhingra, PM Thangaraj… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background: SGLT2 inhibitors (SGLT2is) and GLP-1 receptor agonists (GLP1-RAs) reduce
major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus …