Oxygen therapy can be delivered using low-flow, intermediate-flow (air entrainment mask),
or high-flow devices. Low/intermediate-flow oxygen devices have several drawbacks that …

In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …

Nasal drug delivery has been employed as an alternate and convenient route for the
systemic availability of pharmaceuticals, particularly for potent therapeutics. This is owing to …

Drug dosing in critically ill patients is challenging due to the altered drug pharmacokinetics–
pharmacodynamics associated with systemic therapies. For many drug therapies, there is …

Focusing on the particle deposition due to gravitational sedimentation and inertial impaction,
the transport and deposition of micron particles with various diameters (ie, 1 to 7 μm) have …

Additive Manufacturing (AM) comprises a variety of techniques that enable fabrication of
customised objects with specific attributes. The versatility of AM procedures and constant …

Nebulizers have a number of advantages for the delivery of inhaled pharmaceutical
aerosols, including the use of aqueous formulations and the ability to deliver process …

Validation of a computational fluid dynamics (CFD) model used to simulate turbulent
exchange in an anatomically detailed human upper airway with realistic breathing states is …