Molecular architecture of chitin and chitosan-dominated cell walls in zygomycetous fungal pathogens by solid-state NMR

Q Cheng, MC Dickwella Widanage, JR Yarava… - Nature …, 2024 - nature.com
Zygomycetous fungal infections pose an emerging medical threat among individuals with
compromised immunity and metabolic abnormalities. Our pathophysiological understanding …

New Vision of Cell Walls in Aspergillus fumigatus from Solid-State NMR Spectroscopy

I Gautam, K Singh, MC Dickwella Widanage… - Journal of Fungi, 2024 - mdpi.com
The fungal cell wall plays a critical role in regulating cellular integrity and communication,
and serves as a frontline defense against stress. It is also a prime target for the development …

Comparative analysis of polysaccharide and cell wall structure in Aspergillus nidulans and Aspergillus fumigatus by solid-state NMR

I Gautam, JR Yarava, Y Xu, R Li, FJ Scott… - Carbohydrate …, 2025 - Elsevier
Invasive aspergillosis poses a significant threat to immunocompromised patients, leading to
high mortality rates associated with these infections. Targeting the biosynthesis of cell wall …

Aspergillus nidulans cell wall integrity kinase, MpkA, impacts cellular phenotypes that alter mycelial-material mechanical properties

K Gray, H Edwards, AG Doan, W Huso, JH Lee… - Fungal Biology and …, 2024 - Springer
Mycelial materials are an emerging, natural material made from filamentous fungi that have
the potential to replace unsustainable materials used in numerous commercial applications …