The human DEAD-box protein DDX3X is an RNA remodelling enzyme that has been
implicated in various aspects of RNA metabolism. In addition, like many DEAD-box proteins …

Viruses depend on host cellular resources to replicate. Interaction between viral and host
proteins is essential for the pathogens to ward off immune responses as well as for virus …

Coronavirus has brought about three massive outbreaks in the past two decades. Each step
of its life cycle invariably depends on the interactions among virus and host molecules. The …

Summary G3BP1/2 are paralogous proteins that promote stress granule formation in
response to cellular stresses, including viral infection. The nucleocapsid (N) protein of …

Stress granules (SGs) are cytoplasmic condensates that often form as part of the cellular
antiviral response. Despite the growing interest in understanding the interplay between SGs …

Considerable progress has been made in understanding the molecular host-virus battlefield
during SARS-CoV-2 infection. Nevertheless, the assembly and egress of newly formed …

The innate immune response to viruses is critical for the correct establishment of protective
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the largest RNA
genome, approximately 30 kb, among RNA viruses. The DDX DEAD box RNA helicase is a …

The coronavirus SARS-CoV-2 has caused a health care crisis all over the world since the
end of 2019. Although vaccines and neutralizing antibodies have been developed, rapidly …

DDX3 is a cellular ATP-dependent RNA helicase involved in different aspects of RNA
metabolism ranging from transcription to translation and therefore, DDX3 participates in the …