Metabolomics in gestational diabetes mellitus: A review

XIE Jiewen, LI Ling, X Haoyue - Clinica Chimica Acta, 2023 - Elsevier
Gestational diabetes mellitus (GDM), a common complication of pregnancy, is a type of
diabetes that is first detected and diagnosed during pregnancy. The incidence of GDM is …

Multigenerational diabetes mellitus

JM Thornton, NM Shah, KA Lillycrop, W Cui… - Frontiers in …, 2024 - frontiersin.org
Gestational diabetes (GDM) changes the maternal metabolic and uterine environment, thus
increasing the risk of short-and long-term adverse outcomes for both mother and child …

Liver biomarkers, lipid metabolites, and risk of gestational diabetes mellitus in a prospective study among Chinese pregnant women

P Wu, Y Wang, Y Ye, X Yang, Y Huang, Y Ye, Y Lai… - BMC medicine, 2023 - Springer
Background Liver plays an important role in maintaining glucose homeostasis. We aimed to
examine the associations of liver enzymes and hepatic steatosis index (HSI, a reliable …

Population-based plasma lipidomics reveals developmental changes in metabolism and signatures of obesity risk: a mother-offspring cohort study

SA Mir, L Chen, S Burugupalli, B Burla, S Ji, AAT Smith… - BMC medicine, 2022 - Springer
Background Lipids play a vital role in health and disease, but changes to their circulating
levels and the link with obesity remain poorly characterized in expecting mothers and their …

Altered lipid metabolism in obese women with gestational diabetes and associations with offspring adiposity

S Furse, A Koulman, SE Ozanne… - The Journal of …, 2022 - academic.oup.com
Context Gestational diabetes (GDM) affects 20 million women/year worldwide and is
associated with childhood obesity. Infants of affected mothers have increased adiposity from …

Maternal diet quality and associations with plasma lipid profiles and pregnancy-related cardiometabolic health

PF Van Der Pligt, K Kuswara, SA McNaughton… - European Journal of …, 2023 - Springer
Purpose To assess the relationship of early pregnancy maternal diet quality (DQ) with
maternal plasma lipids and indicators of cardiometabolic health, including blood pressure …

Serum ceramides in early pregnancy as predictors of gestational diabetes

S Mustaniemi, E Keikkala, E Kajantie, M Nurhonen… - Scientific Reports, 2023 - nature.com
Ceramides contribute to the development of type 2 diabetes but it is uncertain whether they
predict gestational diabetes (GDM). In this multicentre case–control study including 1040 …

Mendelian randomization analysis reveals causal effects of blood lipidome on gestational diabetes mellitus

Y Dong, A Hu, B Han, M Cao, H Liu, Z Li, Q Li… - Cardiovascular …, 2024 - Springer
Background Observational studies have revealed associations between maternal lipid
metabolites and gestational diabetes mellitus (GDM). However, whether these associations …

Metabolites involved in purine degradation, insulin resistance, and fatty acid oxidation are associated with prediction of Gestational diabetes in plasma

LE McMichael, H Heath, CM Johnson, R Fanter… - Metabolomics, 2021 - Springer
Introduction Gestational diabetes mellitus (GDM) significantly increases maternal and fetal
health risks, but factors predictive of GDM are poorly understood. Objectives Plasma …

The role of lipid dysregulation in gestational diabetes mellitus: Early prediction and postpartum prognosis

Z Zhang, Z Zhou, H Li - Journal of Diabetes Investigation, 2024 - Wiley Online Library
Gestational diabetes mellitus (GDM) is a pathological condition during pregnancy
characterized by impaired glucose tolerance, and the failure of pancreatic beta‐cells to …