Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …
Bioprinting for the biologist
Building tissues from scratch to explore entirely new cell configurations could revolutionize
fundamental understanding in biology. Bioprinting is an emerging technology to do this …
fundamental understanding in biology. Bioprinting is an emerging technology to do this …
Recapitulating macro-scale tissue self-organization through organoid bioprinting
Bioprinting promises enormous control over the spatial deposition of cells in three
dimensions,,,,,–, but current approaches have had limited success at reproducing the …
dimensions,,,,,–, but current approaches have had limited success at reproducing the …
Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues
The generation of organoids and tissues with programmable cellular complexity,
architecture and function would benefit from the simultaneous differentiation of human …
architecture and function would benefit from the simultaneous differentiation of human …
Engineering stem cell self-organization to build better organoids
JA Brassard, MP Lutolf - Cell stem cell, 2019 - cell.com
Organoids form through self-organization processes in which initially homogeneous
populations of stem cells spontaneously break symmetry and undergo in-vivo-like pattern …
populations of stem cells spontaneously break symmetry and undergo in-vivo-like pattern …
The concept of scaffold-guided bone regeneration for the treatment of long bone defects: current clinical application and future perspective
The treatment of bone defects remains a challenging clinical problem with high
reintervention rates, morbidity, and resulting significant healthcare costs. Surgical …
reintervention rates, morbidity, and resulting significant healthcare costs. Surgical …
Helical polymers for biological and medical applications
T Leigh, P Fernandez-Trillo - Nature Reviews Chemistry, 2020 - nature.com
Helices are the most prevalent secondary structure in biomolecules and play vital roles in
their activity. Chemists have been fascinated with mimicking this molecular conformation …
their activity. Chemists have been fascinated with mimicking this molecular conformation …
Mesoscale physical principles of collective cell organization
We review recent evidence showing that cell and tissue dynamics are governed by
mesoscale physical principles. These principles can be understood in terms of simple state …
mesoscale physical principles. These principles can be understood in terms of simple state …
[HTML][HTML] Responsive inverse opal scaffolds with biomimetic enrichment capability for cell culture
Abstract Three-dimensional (3D) porous scaffolds have a demonstrated value for tissue
engineering and regenerative medicine. Inspired by the predation processes of marine …
engineering and regenerative medicine. Inspired by the predation processes of marine …
Perspective: The promise of multi-cellular engineered living systems
Recent technological breakthroughs in our ability to derive and differentiate induced
pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all …
pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all …