Messenger RNA synthesis by the DNA tumour viruses proceeds by a complex but versatile
series of transcription and RNA processing steps. The major mechanistic features of this …

Publisher Summary The essential feature of a virus is its nucleic acid genome, a cluster of
genes that brings new information into the cell it infects. Depending on the circumstances of …

The discovery of adenoviruses naturally induced a new interest in viruses of the human
upper respiratory tract since previously unknown viruses infecting this portion of the human …

Five host-range mutants(Ad2hr400-hr403, Ad5hr404) of human adenovirus serotype 2 and
5 (Ad2 and Ad5) which overcome the block to growth of wild-type adenovirus in monkey …

The block to adenovirus 2 (Ad2) multiplication in monkey cells can be overcome by
coinfection with simian virus 40 (SV40). To identify this block we have compared the …

Coinfection of monkey cells with simian virus 40 (SV40) and adenovirus type 2 (Ad2)
increased the Ad2 yield 1,000-fold over that obtained by Ad2 infection alone of monkey cells …

In his biography “Arrow in the Blue” the author Arthur Koestler suggests ironically that the
fate of an individual may be predicted by examining the content of the newspapers at birth …

Monkey cells are non-permissive hosts for human adenoviruses due to a block in the
synthesis of certain late viral proteins. Analysis of the RNA produced in abortively infected …

As an initial step toward understanding the mechanisms underlying host cell restriction of
adenovirus 2 (Ad2) replication, we have studied various cell lines derived from hamster …

Human adenovirus fails to multiply efficiently in monkey cells owing to a block to late viral
gene expression. Ad2hr400 through Ad2hr403 are a set of host range (hr) mutants which …