Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

Background: Sepsis is a serious clinical condition characterized by damage to the immune
system as a result of an uncontrolled response to infection. Septic patients show …

Sepsis is a dysregulated systemic reaction to a common infection, that can cause life-
threatening organ dysfunction. Over the last decade, the mortality rate of patients with sepsis …

A healthy body activates the immune response to target invading pathogens (ie viruses,
bacteria, fungi, and parasites) and avoid further systemic infection. The activation of …

Background Long non-coding RNA (lncRNA) cancer susceptibility candidate 9 (CASC9) is
reported to be linked to cancers. This research aims to explore the role and possible …

Sepsis-associated encephalopathy (SAE) is a neurological complication of sepsis,
characterized by brain dysfunction without any direct central nervous system infection. The …

Sepsis and septic shock are still one of the most important medical challenges. Sepsis is an
extreme and uncontrolled response of the innate immune system to invading pathogenesis …

In sepsis, platelets may become activated via toll-like receptors (TLRs), causing
microvascular thrombosis. Megakaryocytes (MKs) also express these receptors; thus, severe …

In addition to the key role in hemostasis and thrombosis, platelets have also been wildly
acknowledged as immune regulatory cells and involving in the pathogenesis of …

To screen out potential prognostic hub genes for adult patients with sepsis via RNA
sequencing and construction of a microRNA–mRNA–PPI network and investigate the …