[HTML][HTML] Nuclear miRNAs: gene regulation activities

M Billi, E De Marinis, M Gentile, C Nervi… - International Journal of …, 2024 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs which contribute to the regulation of many
physiological and pathological processes. Conventionally, miRNAs perform their activity in …

Integrating functional scoring and regulatory data to predict the effect of non-coding SNPs in a complex neurological disease

D Felício, M Alves-Ferreira, M Santos… - Briefings in …, 2024 - academic.oup.com
Most SNPs associated with complex diseases seem to lie in non-coding regions of the
genome; however, their contribution to gene expression and disease phenotype remains …

[HTML][HTML] Emerging roles of non-coding RNAs in colorectal cancer oxaliplatin resistance and liquid biopsy potential

ZD Luo, YF Wang, YX Zhao, LC Yu, T Li… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common malignancies of the digestive tract, with
the annual incidence and mortality increasing consistently. Oxaliplatin-based chemotherapy …

[HTML][HTML] Dual Role of microRNA-146a in Experimental Inflammation in Human Pulmonary Epithelial and Immune Cells and Expression in Inflammatory Lung Diseases

L Gronau, RP Duecker, SP Jerkic, O Eickmeier… - International Journal of …, 2024 - mdpi.com
microRNA (miR)-146a emerges as a promising post-transcriptional regulator in various
inflammatory diseases with different roles for the two isoforms miR-146a-5p and miR-146a …

[HTML][HTML] Deciphering the Molecular Mechanism of Incurable Muscle Disease by a Novel Method for the Interpretation of miRNA Dysregulation

D Israeli, A Vu Hong, G Corre, Q Miagoux, I Richard - Non-coding RNA, 2022 - mdpi.com
It is now well-established that microRNA dysregulation is a hallmark of human diseases, and
that aberrant expression of miRNA is not randomly associated with human pathologies but …

[HTML][HTML] Noncanonical functions of microRNAs in the nucleus: Noncanonical functions of microRNAs in the nucleus

J Gu, Y Li, Y Tian, Y Zhang, Y Cheng… - Acta Biochimica et …, 2024 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small noncoding RNAs (ncRNAs) that play their roles in the
regulation of physiological and pathological processes. Originally, it was assumed that …

Circulating miRNAs as biomarkers of toxic heavy metal exposure

AN Nail, AP Ferragut Cardoso… - … of Toxicology and …, 2022 - Wiley Online Library
Heavy metal exposure, for example arsenic, lead, mercury, cadmium, and chromium
exposure, can cause various health issues such as multiple organ damage, cardiovascular …

[HTML][HTML] miR-145-3p Inhibits MuSCs Proliferation and Mitochondria Mass via Targeting MYBL1 in Jianzhou Big-Eared Goats

E Odame, L Li, JA Nabilla, H Cai, M Xiao, J Ye… - International Journal of …, 2023 - mdpi.com
Muscle growth and injury-induced regeneration are controlled by skeletal muscle satellite
cells (MuSCs) through myogenesis in postnatal animals. Meanwhile, myogenesis is …

Optimization of Cdx transcription factors characteristics

T Javanbakht - 2023 - essuir.sumdu.edu.ua
This study presents a new application of TOPSIS for the optimization of transcription factors
characteristics. This application is essential as it can help compare the characteristics of …

[PDF][PDF] Nuclear microRNAs: the role of miR-466c in transcriptional gene activation

P Laitinen - 2023 - erepo.uef.fi
Ischemic diseases are a diverse group of diseases that occur due to the lack of oxygen and
nutrients reaching the tissues (ie, ischemia). Ischemic stroke and ischemic heart disease are …