Revisiting the virulence hallmarks of Pseudomonas aeruginosa: a chronicle through the perspective of quorum sensing

J Chadha, K Harjai, S Chhibber - Environmental microbiology, 2022 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …

Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review

A Grace, R Sahu, DR Owen, VA Dennis - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa is a ubiquitous, motile, gram-negative bacterium that has been
recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics. Of …

Pseudomonas aeruginosa breaches respiratory epithelia through goblet cell invasion in a microtissue model

AL Swart, BJ Laventie, R Sütterlin, T Junne… - Nature …, 2024 - nature.com
Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

[HTML][HTML] Pseudomonas aeruginosa: an antibiotic resilient pathogen with environmental origin

P Laborda, F Sanz-García, S Hernando-Amado… - Current Opinion in …, 2021 - Elsevier
Highlights•P. aeruginosa is opportunistic pathogen with an environmental origin.•P.
aeruginosa presents low susceptibility to currently used antibiotics.•P. aeruginosa displays a …

[HTML][HTML] Type 3 secretion system of Pseudomonas aeruginosa

G Horna, J Ruiz - Microbiological Research, 2021 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen, mainly affecting severe patients,
such as those in intensive care units (ICUs). High levels of antibiotic resistance and a long …

Genome-driven elucidation of phage-host interplay and impact of phage resistance evolution on bacterial fitness

P Markwitz, C Lood, T Olszak, V van Noort… - The ISME …, 2022 - academic.oup.com
When considering the interactions between bacteriophages and their host, the issue of
phage-resistance emergence is a key element in understanding the ecological impact of …

ESKAPE pathogens: antimicrobial resistance, epidemiology, clinical impact and therapeutics

WR Miller, CA Arias - Nature Reviews Microbiology, 2024 - nature.com
The rise of antibiotic resistance and a dwindling antimicrobial pipeline have been
recognized as emerging threats to public health. The ESKAPE pathogens—Enterococcus …

Current status of pan-genome analysis for pathogenic bacteria

Y Kim, C Gu, HU Kim, SY Lee - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Wealth of genome data are making pan-genome analysis increasingly
possible.•Pan-genome analysis is an effective approach to understand pathogenic …

Current concepts on Pseudomonas aeruginosa interaction with human airway epithelium

A Muggeo, C Coraux, T Guillard - PLoS pathogens, 2023 - journals.plos.org
Pseudomonas aeruginosa is a major, but opportunistic, respiratory pathogen, which rarely
infects healthy individuals, mainly due to the barrier effect of the human airway epithelium …

Pseudomonas aeruginosa Biofilm Dispersion by the Human Atrial Natriuretic Peptide

M Louis, T Clamens, A Tahrioui, F Desriac… - Advanced …, 2022 - Wiley Online Library
Pseudomonas aeruginosa biofilms cause chronic, antibiotic tolerant infections in wounds
and lungs. Numerous recent studies demonstrate that bacteria can detect human …