Systemic amyloidosis is a rare protein misfolding and deposition disorder leading to
progressive organ failure. There are over 15 types of systemic amyloidosis, each caused by …

Cardiac amyloidosis is a serious and progressive infiltrative disease that is caused by the
deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the …

Genetic, environmental, and aging-related insults can promote the misfolding and
subsequent aggregation of secreted proteins implicated in the pathogenesis of numerous …

Cardiac amyloidosis is a serious and progressive infiltrative disease that is caused by the
deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the …

Extracellularly released molecular inflammasome assemblies-ASC specks-cross-seed Aβ
amyloid in Alzheimer's disease. Here we show that ASC governs the extent of inflammation …

The crosstalk between viral infections, amyloid formation and neurodegeneration has been
discussed with varying intensity since the last century. Several viral proteins are known to be …

The epidemiology of cardiac amyloidosis (CA), traditionally considered a rare and incurable
disease, has changed drastically over the last ten years, particularly due to the advances in …

Alzheimer's disease (AD), diabetes mellitus (DM), inflammatory bowel diseases (IBD), and
rheumatoid arthritis (RA) are chronic conditions affecting millions globally. Despite differing …

Amyloidosis is a protein folding disease that causes organ injuries and even death. In
humans, 42 proteins are now known to cause amyloidosis. Some proteins become …

Amyloid A amyloidosis is a serious clinical condition resulting from the systemic deposition
of amyloid A originating from serum amyloid A proteins with the kidneys being the most …