Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

As one of the most prevalent neurotrophic factors in the central nervous system (CNS), brain-
derived neurotrophic factor (BDNF) plays a significant role in CNS injury by binding to its …

Accumulating evidence suggests that the gut microbiome influences the brain functions and
psychological state of its host via the gut–brain axis, and gut dysbiosis has been linked to …

Abstract DL-3-n-Butylphthalide (DL-NBP), a small molecular compound extracted from the
seeds of Apium graveolens Linn (Chinese celery), has been shown to exert neuroprotective …

Heart failure (HF) is a chronic, complex condition with increasing incidence worldwide,
necessitating the development of novel therapeutic strategies. This has led to the current …

Brain-derived neurotrophic factor (BDNF) is one of the most abundant neurotrophins in the
central nervous system. Numerous studies suggest that BDNF has extensive roles by …

In-depth characterization of heart-brain communication in critically ill patients with severe
acute respiratory failure is attracting significant interest in the COronaVIrus Disease 19 …

Purpose Divers can experience cognitive impairment due to inert gas narcosis (IGN) at
depth. Brain-derived neurotrophic factor (BDNF) rules neuronal connectivity/metabolism to …

By definition, heart failure (HF) is a pathological condition affecting the structure and function
of all organs in the body, and the brain is not an exception to that. Failure of the heart to …

Obesity arising from excessive dietary fat intake is a risk factor for cognitive decline,
dementia and neurodegenerative diseases, including Alzheimer's disease. Here, we studied …