Highly active anti-retroviral therapy (HAART) is prescribed for HIV infection and, to a certain
extent, limits the infection's spread. However, it cannot completely eradicate the latent virus …

Abstract The advent of Highly Active Antiretroviral Therapy has majorly contributed towards
reducing the morbidity and mortality associated with HIV infected people, thus improving the …

Background & Aims Celiac disease could be treated, and potentially cured, by restoring T-
cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged 500 …

Inflammation associated with autoimmune diseases and chronic injury is an initiating event
that leads to tissue degeneration and dysfunction. Inflammatory monocytes and neutrophils …

Cutaneous leishmaniasis (CL) is an infectious, parasitic disease caused by the protozoan
Leishmania. Amphotericin B (AMB) is a macrolide polyene antibiotic presenting potent …

Effective induction of an antigen-specific cytotoxic T lymphocyte (CTL) immune response is
one of the key goals of cancer immunotherapy. We report the design and fabrication of …

Inspired by the immune system's own strategy for macrophage activation, we describe here
a simple self-assembly strategy for generating artificial immune complexes. The built-in …

A plethora of biological barriers, intended to defend tissues and cells against external
influences, stand in the way of efficient nucleic acid delivery by non-viral nanoplexes. Even …

Nontuberculous mycobacteria (NTM) represent an increasingly prevalent etiology of soft
tissue infections in animals and humans. NTM are widely distributed in the environment and …

Percutaneous coronary intervention (PCI) is a common procedure for the management of
coronary artery obstruction. However, it usually causes vascular wall injury leading to …