Liquid‐assisted grinding mechanochemistry in the synthesis of pharmaceuticals

P Ying, J Yu, W Su - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
Mechanochemical reactions by milling, grinding or other types of mechanical action have
emerged as a salient green approach because of its wide applications towards academic …

Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: A mini-review

G Yadav, S Ganguly - European journal of medicinal chemistry, 2015 - Elsevier
Benzimidazoles are the fused heterocyclic ring systems which form an integral part of
vitamin B 12 and have been luring many researchers all over the world to assess their …

K10 montmorillonite clays as environmentally benign catalysts for organic reactions

BS Kumar, A Dhakshinamoorthy… - Catalysis Science & …, 2014 - pubs.rsc.org
Montmorillonite is one of the most intensively explored catalytic materials in heterogeneous
catalysis due to its low cost and eco-friendliness. Also, it possesses some unique properties …

Recent advances in the synthesis of 2-substituted benzothiazoles: a review

NP Prajapati, RH Vekariya, MA Borad, HD Patel - Rsc Advances, 2014 - pubs.rsc.org
Benzothiazole can serve as unique and versatile scaffolds, especially in synthetic and
pharmaceutical chemistry because of their potent and significant pharmacological activities …

Copper-catalyzed synthesis of substituted benzothiazoles via condensation of 2-aminobenzenethiols with nitriles

Y Sun, H Jiang, W Wu, W Zeng, X Wu - Organic letters, 2013 - ACS Publications
An efficient and convenient method was developed for the formation of 2-substituted
benzothiazoles via a copper-catalyzed condensation of 2-aminobenzenethiols with nitriles …

Iron sulfide catalyzed redox/condensation cascade reaction between 2-amino/hydroxy nitrobenzenes and activated methyl groups: a straightforward atom economical …

TB Nguyen, L Ermolenko… - Journal of the American …, 2013 - ACS Publications
Iron sulfide generated in situ from elemental sulfur and iron was found to be highly efficient
in catalyzing a redox/condensation cascade reaction between 2-amino/hydroxy …

Cobalt- and Iron-Catalyzed Redox Condensation of o-Substituted Nitrobenzenes with Alkylamines: A Step- and Redox-Economical Synthesis of Diazaheterocycles

TB Nguyen, J Le Bescont, L Ermolenko… - Organic …, 2013 - ACS Publications
A wide variety of functionalized 2-aryl benzimidazoles can be prepared by a solvent-free
cobalt-or iron-catalyzed redox condensation of 2-nitroanilines and benzylamines. The …

A Review of Approaches to the Metallic and Non-Metallic Synthesis of Benzimidazole (BnZ) and Their Derivatives for Biological Efficacy

M Patel, G Avashthi, A Gacem, MS Alqahtani, HK Park… - Molecules, 2023 - mdpi.com
Heterocyclic compounds are significant lead drug candidates based on their various
structure–activity relationships (SAR), and their use in pharmaceutics is constantly …

Metal- and Oxidant-Free Synthesis of Quinazolinones from β-Ketoesters with o-Aminobenzamides via Phosphorous Acid-Catalyzed Cyclocondensation and …

Z Li, J Dong, X Chen, Q Li, Y Zhou… - The Journal of Organic …, 2015 - ACS Publications
A general and efficient phosphorous acid-catalyzed cyclocondensation of β-ketoesters with
o-aminobenzamides via selective C–C bond cleavage leading to quinazolinones is …

Synthesis of benz-fused azoles via C-heteroatom coupling reactions catalyzed by Cu (I) in the presence of glycosyltriazole ligands

N Mishra, AS Singh, AK Agrahari… - ACS Combinatorial …, 2019 - ACS Publications
Glycosyl triazoles are conveniently accessible and contain multiple metal-binding units that
may assist in metal-mediated catalysis. Azide derivatives of d-glucose have been converted …