Dengue

A Wilder-Smith, EE Ooi, O Horstick, B Wills - The Lancet, 2019 - thelancet.com
Mortality from severe dengue is low, but the economic and resource burden on health
services remains substantial in endemic settings. Unfortunately, progress towards …

Congenital Zika syndrome: A systematic review

DA Freitas, R Souza-Santos, LMA Carvalho… - PLoS …, 2020 - journals.plos.org
Background The signs and symptoms of Zika virus infection are usually mild and self-limited.
However, the disease has been linked to neurological complications such as Guillain-Barré …

[PDF][PDF] How to design vector control efficacy trials: guidance on phase III vector control field trial design provided by the Vector Control Advisory Group

World Health Organization - 2017 - apps.who.int
Vector-borne diseases (VBDs), including malaria, dengue and leishmaniasis, cause
considerable morbidity and mortality in tropical regions of the world. Vector control methods …

Epidemic arboviral diseases: priorities for research and public health

A Wilder-Smith, DJ Gubler, SC Weaver… - The Lancet infectious …, 2017 - thelancet.com
For decades, arboviral diseases were considered to be only minor contributors to global
mortality and disability. As a result, low priority was given to arbovirus research investment …

Challenges and opportunities in controlling mosquito-borne infections

NM Ferguson - Nature, 2018 - nature.com
Mosquito-borne diseases remain a major cause of morbidity and mortality across the tropical
regions. Despite much progress in the control of malaria, malaria-associated morbidity …

Urbanization creates diverse aquatic habitats for immature mosquitoes in urban areas

ABB Wilke, C Chase, C Vasquez, A Carvajal… - Scientific reports, 2019 - nature.com
Global increases in temperatures and urbanization are impacting the epidemiology of
mosquito-borne diseases. Urbanization processes create suitable habitats for vector …

NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models

SA Moquin, O Simon, R Karuna… - Science translational …, 2021 - science.org
Dengue virus (DENV) is a mosquito-borne flavivirus that poses a threat to public health, yet
no antiviral drug is available. We performed a high-throughput phenotypic screen using the …

Prevention and control of dengue—the light at the end of the tunnel

T Pang, TK Mak, DJ Gubler - The Lancet Infectious Diseases, 2017 - thelancet.com
Advances in the development of new dengue control tools, including vaccines and vector
control, herald a new era of desperately needed dengue prevention and control. The burden …

Indoor Resting Behavior of Aedes aegypti (Diptera: Culicidae) in Acapulco, Mexico

F Dzul-Manzanilla, J Ibarra-López… - Journal of medical …, 2017 - academic.oup.com
The markedly anthropophilic and endophilic behaviors of Aedes aegypti (L.) make it a very
efficient vector of dengue, chikungunya, and Zika viruses. Although a large body of research …

A systematic review of mathematical models of dengue transmission and vector control: 2010–2020

ST Ogunlade, MT Meehan, AI Adekunle, ES McBryde - Viruses, 2023 - mdpi.com
Vector control methods are considered effective in averting dengue transmission. However,
several factors may modify their impact. Of these controls, chemical methods, in the long run …