Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to
failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms …

Bronchiectasis is a clinical and radiological diagnosis associated with cough, sputum
production and recurrent respiratory infections. The clinical presentation inevitably overlaps …

Background Bronchiectasis is a heterogeneous, neglected disease with few multicentre
studies exploring the causes, severity, microbiology, and treatment of the disease across …

Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent
exacerbations in many patients. There have been no previous international guidelines. The …

Background Bronchiectasis is a common but neglected chronic lung disease. Most
epidemiological data are limited to cohorts from Europe and the USA, with few data from low …

Abstract 16S rRNA gene profiling, which contains nine hypervariable regions (V1–V9), is the
gold standard for identifying taxonomic units by high-throughput sequencing. Microbiome …

Chronic lung diseases are the third leading cause of death worldwide and are increasing in
prevalence over time. Although much of our traditional understanding of health and disease …

Summary European Respiratory Society guidelines for the management of adult
bronchiectasis highlight the paucity of treatment options available for patients with this …

Bronchiectasis is a disease of renewed interest in light of an increase in prevalence and
increasing burden on international healthcare systems. There are no licensed therapies …

Introduction Bronchiectasis is a multidimensional disease associated with substantial
morbidity and mortality. Two disease-specific clinical prediction tools have been developed …