We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

The authors identified individual randomized controlled trials from previous meta-analyses
and additional searches, and then performed meta-analyses on cardiovascular disease …

The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

Importance The associations of serum folate and vitamin B 12 levels with cardiovascular
outcomes among patients with type 2 diabetes (T2D) remain unclear. Objective To …

Importance Uncertainty remains about the efficacy of folic acid therapy for the primary
prevention of stroke because of limited and inconsistent data. Objective To test the primary …

Background and Purpose—This guideline provides an overview of the evidence on
established and emerging risk factors for stroke to provide evidence-based …

Homocysteine (Hcy) is a thiol group containing the amino acid, which naturally occurs in all
humans. Hcy is degraded in the body through two metabolic pathways, while a minor part is …

Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Background Results from observational and genetic epidemiological studies suggest that
lower serum homocysteine levels are associated with lower incidence of cardiovascular …

Dietary supplements are widely used and offer the potential to improve health if
appropriately targeted to those in need. Inadequate nutrition and micronutrient deficiencies …