Currently, the efficacy of antibiotics is severely affected by the emergence of the
antimicrobial resistance phenomenon, leading to increased morbidity and mortality …

Infective endocarditis, osteomyelitis, and osteosynthesis-associated infections are mostly
caused by Gram-positive bacteria. They are often difficult to treat and are associated with a …

Background Antimicrobial resistance is a global issue that causes significant morbidity and
mortality. Therefore, this study aims to assess knowledge, attitudes, and practices (KAP) of …

Skin and soft tissue infections (SSTI) along with bone and joint infections represent a
significant source of morbidity and mortality among people who inject drugs (PWID) …

Acute bacterial skin and soft tissue infections (aSSTIs) are a large group of diseases that can
involve exclusively the skin or also the underlying subcutaneous tissues, fascia, or muscles …

Objectives To investigate the clinical efficacy and safety of ceftobiprole for acute bacterial
skin and skin structure infections (ABSSSIs). Methods PubMed, Web of Science, EBSO, Ovid …

Fluoroquinolones are known widely used synthetic antibacterial agents. Generally, there
were some obstacles associated with their therapeutic use. Moreover, many research …

Purpose To evaluate the efficacy and safety of oral sitafloxacin versus levofloxacin in
Chinese adults with acute uncomplicated urinary tract infection (UTI) or complicated UTI …

Staphylococcus aureus is a Gram-positive bacterium, which can cause serious bacterial
infections in humans. It constitutes an important etiological factor of many diseases, for …

Necrotizing soft tissue infections (NSTIs) are severe, life-threatening infections, and early
therapeutic intervention is essential. Prompt administration of potent antimicrobial agents is …