Metal complexes against breast cancer stem cells

Y Li, B Liu, H Shi, Y Wang, Q Sun, Q Zhang - Dalton Transactions, 2021 - pubs.rsc.org
With the highest incidence, breast cancer is the leading cause of cancer deaths among
women in the world. Tumor metastasis is the major contributor of high mortality in breast …

Molecular chaperones in cancer stem cells: determinants of stemness and potential targets for antitumor therapy

A Kabakov, A Yakimova, O Matchuk - Cells, 2020 - mdpi.com
Cancer stem cells (CSCs) are a great challenge in the fight against cancer because these
self-renewing tumorigenic cell fractions are thought to be responsible for metastasis …

Triorganotin (IV) complexes of Schiff base derived from 1, 2, 4-triazole moiety: Synthesis, spectroscopic investigation, DFT studies, antifungal activity and molecular …

R Joshi, A Kumari, K Singh, H Mishra… - Journal of Molecular …, 2020 - Elsevier
New triorganotin (IV) complexes of Schiff base (E)-4-amino-3-(2-(4-hydroxybenzylidene)
hydrazinyl)-1H-1, 2, 4-triazole-5 (4H)-thione (HL) with general formula R 3 SnL (where L is …

HSP70s in breast cancer: promoters of tumorigenesis and potential targets/tools for therapy

AE Kabakov, VL Gabai - Cells, 2021 - mdpi.com
The high frequency of breast cancer worldwide and the high mortality among women with
this malignancy are a serious challenge for modern medicine. A deeper understanding of …

Heat Shock Proteins and Breast Cancer

M Zhang, X Bi - International Journal of Molecular Sciences, 2024 - mdpi.com
Heat shock proteins (Hsps) are a group of stress-induced proteins involved in protein folding
and maturation. Based on their molecular weight, Hsps can be divided into six families …

[HTML][HTML] Limonin attenuates the stemness of breast cancer cells via suppressing MIR216A methylation

Z Su, C Wang, D Chang, X Zhu, C Sai, J Pei - Biomedicine & …, 2019 - Elsevier
Limonin has been shown to exert anti-inflammatory effects, however, its roles in tumor
progression remain unclear. This work aims to investigate the roles and related mechanism …

Short peptide domains of the Wnt inhibitor sFRP4 target ovarian cancer stem cells by neutralizing the Wnt β-catenin pathway, disrupting the interaction between β …

SM Sundaram, L Varier, KZ Fathima, A Dharmarajan… - Life Sciences, 2023 - Elsevier
Aims One of the hallmarks of cancer stem cells (CSC) is hyperactive Wnt β-catenin signaling
due to the decreased presence of Wnt antagonists such as secreted frizzled related protein …

Inhibition of human prostate cancer (PC-3) cells and targeting of PC-3-derived prostate cancer stem cells with koenimbin, a natural dietary compound from Murraya …

B Kamalidehghan, S Ghafouri-Fard… - Drug design …, 2018 - Taylor & Francis
Background Inhibition of prostate cancer stem cells (PCSCs) is an efficient curative
maintenance protocol for the prevention of prostate cancer. The objectives of this study were …

A bright horizon of intelligent targeted-cancer therapy: nanoparticles against breast cancer stem cells

A Vaez, M Abbasi, L Shabani… - Current Stem Cell …, 2023 - benthamdirect.com
Breast cancer stem cells (BCSCs) are heterogeneous tumor-initiating cell subgroups of
breast cancers that possess some stem cell markers and are sustained after chemotherapy …

[HTML][HTML] Gomisin M2 from Baizuan suppresses breast cancer stem cell proliferation in a zebrafish xenograft model

Y Yang, E Hao, X Pan, D Tan, Z Du, J Xie, X Hou… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Gomisin M2 isolated from Schisandra viridis AC Smith has potential anti-tumor effects on
certain cancers, including breast cancer. However, only a few investigations have been …