Bacterial pathogens rely on proteolysis for variety of purposes during the infection process. In the cytosol, the main proteolytic players are the conserved Clp and Lon proteases that …
DE Fouts, MA Matthias, H Adhikarla… - PLoS neglected …, 2016 - journals.plos.org
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread, neglected and emerging zoonotic disease. While whole genome analysis of individual …
AJ Laarman, M Ruyken, CL Malone… - The Journal of …, 2011 - journals.aai.org
Complement is one of the first host defense barriers against bacteria. Activated complement attracts neutrophils to the site of infection and opsonizes bacteria to facilitate phagocytosis …
JM Mootz, CL Malone, LN Shaw… - Infection and …, 2013 - Am Soc Microbiol
Staphylococcus aureus is a known cause of chronic biofilm infections that can reside on medical implants or host tissue. Recent studies have demonstrated an important role for …
M Jusko, J Potempa, T Kantyka, E Bielecka… - Journal of innate …, 2014 - karger.com
Staphylococcus aureus is an opportunistic pathogen that presents severe health care concerns due to the prevalence of multiple antibiotic-resistant strains. New treatment …
Bacterial extracellular metalloproteases (BEMPs) are a large group of metal-containing proteases secreted by heterotrophic bacteria. In this review, the diversity, structural …
H Alnaseri, B Arsic, JET Schneider… - Journal of …, 2015 - Am Soc Microbiol
Although Staphylococcus aureus is exposed to antimicrobial fatty acids on the skin, in nasal secretions, and in abscesses, a specific mechanism of inducible resistance to this important …
V Singh, UJ Phukan - Medical Microbiology and Immunology, 2019 - Springer
Staphylococcus aureus causes various health care-and community-associated infections as well as certain chronic TH2 driven inflammatory diseases. It is a potent pathogen with …
C Nwankwo, J Hou, HL Cui - Applied Microbiology and Biotechnology, 2023 - Springer
Halophilic extracellular proteases offer promising application in various fields. Information on these prominent proteins including the synthesizing organisms, biochemical properties …