Characteristics, prevention, and management of cardiovascular disease in people living with HIV: a scientific statement from the American Heart Association
As early and effective antiretroviral therapy has become more widespread, HIV has
transitioned from a progressive, fatal disease to a chronic, manageable disease marked by …
transitioned from a progressive, fatal disease to a chronic, manageable disease marked by …
Hypertension: do inflammation and immunity hold the key to solving this epidemic?
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
The end of AIDS: HIV infection as a chronic disease
The success of antiretroviral therapy has led some people to now ask whether the end of
AIDS is possible. For patients who are motivated to take therapy and who have access to …
AIDS is possible. For patients who are motivated to take therapy and who have access to …
[HTML][HTML] National Lipid Association recommendations for patient-centered management of dyslipidemia: part 2
TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …
a consensus set of recommendations for the patient-centered management of dyslipidemia …
The HIV reservoir in monocytes and macrophages
ME Wong, A Jaworowski, AC Hearps - Frontiers in immunology, 2019 - frontiersin.org
In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
Systemic effects of inflammation on health during chronic HIV infection
Combination antiretroviral therapy for HIV infection improves immune function and
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
Soluble markers of inflammation and coagulation but not T-cell activation predict non–AIDS-defining morbid events during suppressive antiretroviral treatment
AR Tenorio, Y Zheng, RJ Bosch… - The Journal of …, 2014 - academic.oup.com
Background. Defining the association of non–AIDS-defining events with inflammation and
immune activation among human immunodeficiency virus (HIV)–infected persons with …
immune activation among human immunodeficiency virus (HIV)–infected persons with …
Immune activation and HIV persistence: implications for curative approaches to HIV infection
NR Klatt, N Chomont, DC Douek… - Immunological …, 2013 - Wiley Online Library
Despite complete or near‐complete suppression of human immunodeficiency virus (HIV)
replication with combination antiretroviral therapy, both HIV and chronic …
replication with combination antiretroviral therapy, both HIV and chronic …
Microbial translocation in HIV infection: causes, consequences and treatment opportunities
NG Sandler, DC Douek - Nature Reviews Microbiology, 2012 - nature.com
Systemic immune activation is increased in HIV-infected individuals, even in the setting of
virus suppression with antiretroviral therapy. Although numerous factors may contribute …
virus suppression with antiretroviral therapy. Although numerous factors may contribute …
Arterial inflammation in patients with HIV
Context Cardiovascular disease is increased in patients with human immunodeficiency virus
(HIV), but the specific mechanisms are unknown. Objective To assess arterial wall …
(HIV), but the specific mechanisms are unknown. Objective To assess arterial wall …