Hypothermic oxygenated liver perfusion: basic mechanisms and clinical application
A Schlegel, P Kron, P Dutkowski - Current transplantation reports, 2015 - Springer
Dynamic preservation strategies such as hypothermic machine perfusion are increasingly
discussed to improve liver graft quality before transplantation. This review summarizes …
discussed to improve liver graft quality before transplantation. This review summarizes …
[HTML][HTML] How much ischemia can the liver tolerate during resection?
WG van Riel, RF van Golen, MJ Reiniers… - … surgery and nutrition, 2016 - ncbi.nlm.nih.gov
The use of vascular inflow occlusion (VIO, also known as the Pringle maneuver) during liver
surgery prevents severe blood loss and the need for blood transfusion. The most commonly …
surgery prevents severe blood loss and the need for blood transfusion. The most commonly …
Hypo-and normothermic perfusion of the liver: Which way to go?
J Selten, A Schlegel, J de Jonge… - Best practice & research …, 2017 - Elsevier
The demand of donor livers for transplantation exceeds the supply. In an attempt to
maximize the number of potentially usable donor livers, several centers are exploring the …
maximize the number of potentially usable donor livers, several centers are exploring the …
Protective mechanisms of hypothermia in liver surgery and transplantation
PB Olthof, MJ Reiniers, MC Dirkes, TM van Gulik… - Molecular …, 2015 - Springer
Hepatic ischemia/reperfusion (I/R) injury is a side effect of major liver surgery that often
cannot be avoided. Prolonged periods of ischemia put a metabolic strain on hepatocytes …
cannot be avoided. Prolonged periods of ischemia put a metabolic strain on hepatocytes …
[HTML][HTML] Enhancing Liver Transplant Outcomes through Liver Precooling to Mitigate Inflammatory Response and Protect Mitochondrial Function
MH Tran, J Gao, X Wang, R Liu, CL Parris, C Esquivel… - Biomedicines, 2024 - mdpi.com
Transplanted organs experience several episodes of ischemia and ischemia-reperfusion.
The graft injury resulting from ischemia-reperfusion (IRI) remains a significant obstacle to the …
The graft injury resulting from ischemia-reperfusion (IRI) remains a significant obstacle to the …
Advances in hypothermic perfusion
PA Clavien, P Dutkowski - Liver Transplantation, 2017 - journals.lww.com
1. Machine perfusion of explanted organs is an interesting and novel method to repair
injured organs before implantation. 2. Different technologies need to be compared in the …
injured organs before implantation. 2. Different technologies need to be compared in the …
[PDF][PDF] Hypothermic liver perfusion
A Schlegel, P Dutkowski - Liver Transplantation, 2015 - Wiley Online Library
1. Hypothermic liver perfusion needs the presence of oxygenation and low perfusion
pressure. 2. The protective mechanism base on a reversible down-regulation of …
pressure. 2. The protective mechanism base on a reversible down-regulation of …
Cooling Techniques and Ex Situ Liver Surgery
U Cillo, E Gringeri - … and Hepatobiliary Surgery: Interplay of Technical and …, 2020 - Springer
Hypothermic preservation is a strategy to reduce ischemia-reperfusion injury in both liver
transplantation and liver resection procedures and has been successfully used in liver …
transplantation and liver resection procedures and has been successfully used in liver …
[图书][B] Enhancement of liver regeneration and liver surgery
P Olthof - 2017 - pure.uva.nl
Background: Hepatic ischemia/reperfusion (I/R) injury is characterized by hepatocellular
damage, sterile inflammation, and compromised postoperative liver function. Generally used …
damage, sterile inflammation, and compromised postoperative liver function. Generally used …