Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …

The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Invasive fungal infections and systemic mycosis, whether from nosocomial infection or
immunodeficiency, have been on an upward trend for numerous years. Despite …

Invasive fungal infections are becoming an increasingly important cause of human mortality
and morbidity, particularly for immunocompromised populations. The fungal pathogens …

Covering: 2005 to 2007 Natural product and natural product-derived compounds that are
being evaluated in clinical trials or are in registration (as at 31st December 2007) have been …

Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …

Prior to 1981, treatment options for invasive fungal infections were limited and associated
with significant toxicities. The introduction of ketoconazole marked the beginning of an era of …

ABSTRACT Introduction: Invasive fungal diseases (IFDs) are a leading cause of morbidity
and mortality among immunocompromised patients with bone marrow failure syndromes …

Onychomycosis is a frequent nail disease caused by dermatophytes, yeasts, and
nondermatophyte molds. Trichophyton rubrum, T mentagrophytes, and Epidermophyton …