Oral nanomedicine: challenges and opportunities

B Deng, S Liu, Y Wang, B Ali, N Kong, T Xie… - Advanced …, 2024 - Wiley Online Library
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

Marine biomaterials in biomedical nano/micro-systems

Y Wang, L Chen, Y Wang, X Wang, D Qian… - Journal of …, 2023 - Springer
Marine resources in unique marine environments provide abundant, cost-effective natural
biomaterials with distinct structures, compositions, and biological activities compared to …

Biomimetic epigallocatechin gallate–cerium assemblies for the treatment of rheumatoid arthritis

X Song, Z Zheng, S Ouyang, H Chen… - … Applied Materials & …, 2023 - ACS Publications
Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease that is so far
incurable with long-term health risks. The high doses and frequent administration for the …

Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis: Focus on underlying mechanisms and future perspectives

Z Liu, H Liu, J Cheng, H Wang, Y Yang, J Ye… - Chinese Chemical …, 2024 - Elsevier
Ulcerative colitis (UC) is a common progressive inflammatory disease whose incidence has
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …

Intestine‐Targeted Explosive Hydrogel Microsphere Promotes Uric Acid Excretion for Gout Therapy

Y Tang, Y Du, J Ye, L Deng, W Cui - Advanced Materials, 2024 - Wiley Online Library
Uric acid metabolism disorder triggers metabolic diseases, especially gout. However,
increasing uric acid excretion remains a challenge. Here, an accelerative uric acid excretion …

[HTML][HTML] Development of biomedical hydrogels for rheumatoid arthritis treatment

MMFA Baig, LK Wong, AW Zia, H Wu - Asian Journal of Pharmaceutical …, 2024 - Elsevier
Rheumatoid Arthritis (RA) is an autoimmune disorder that hinders the normal functioning of
bones and joints and reduces quality of human life. Every year millions of people are …

Targeting Osteoblast‐Osteoclast Cross‐Talk Bone Homeostasis Repair Microcarriers Promotes Intervertebral Fusion in Osteoporotic Rats

J Zheng, X Li, F Zhang, C Li, X Zhang… - Advanced …, 2024 - Wiley Online Library
Balancing osteoblast‐osteoclast (OB‐OC) cross‐talk is crucial for restoring bone tissue
structure and function. Current clinical drugs targeting either osteogenesis or …

Injectable Gene/Fiber‐Plexes Reverse Adipose Niche Senescence via Mito‐TERT Activation by Endogenous Mitochondrial Translocation

Y Zhang, J He, S Ling, Y Xie, W Xiong… - Advanced Functional …, 2024 - Wiley Online Library
Addressing adipose niche senescence is crucial for preventing obesity‐related aging.
Telomerase reverse transcriptase (TERT) is a promising target for gene therapy, but …

Glutathione-responsive nanoplatforms trigger gaseous intervention of intestinal inflammation through TLR4/MD2/MyD88/NF-κB/iNOS pathway activation and gut …

Y Li, B Zhu, T Chen, L Chen, D Wu, X Wang, D Li… - Chemical Engineering …, 2024 - Elsevier
Overproduction of reactive oxygen species (ROS) is a primary cause of chronic intestinal
inflammation, controlled nanosequence-like drugs with GSH-responsive release have …

Bioinspired and biomimetic strategies for inflammatory bowel disease therapy

L Zhang, P Ye, H Zhu, L Zhu, Y Ren… - Journal of Materials …, 2024 - pubs.rsc.org
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammatory bowel disease with
high morbidity and an increased risk of cancer or death, resulting in a heavy societal …