Although the incidence of endometrial carcinoma (EC) is similar in Black and White women,
racial disparities are stark, with the highest mortality rates observed among Black patients …

Background Racial disparities in outcomes exist in endometrial cancer (EC). The
contribution of ancestry‐based variations in germline pathogenic variants (gPVs) is …

• Cancer staging is an important prognostic criterion and should remain anatomic.• Histology
should not be dichotomized and should not be a part of staging.• Diagnosis/quantification of …

In recent years, next-generation sequencing (NGS)–based genetic testing has become
crucial in cancer care. While its primary objective is to identify actionable genetic alterations …

Background Endometrial cancer (EMC) is the most common female genital tract malignancy
with an increasing prevalence in many countries including Japan, a fact that renders early …

Purpose: Inhibition of the cyclin D–cyclin-dependent kinase (CDK) 4/6–INK4–retinoblastoma
pathway can overcome acquired or de novo treatment resistance to endocrine monotherapy …

Abstract Objective The International Federation of Gynecology and Obstetrics (FIGO) 2023
staging system for endometrial cancer (EC) was released with incorporating histology …

BACKGROUND. Obesity is the foremost risk factor in the development of endometrial cancer
(EC). However, the impact of obesity on the response to immune checkpoint inhibitors (ICI) …

Methods Forty-one carcinosarcomas were identified from a cohort of 973 endometrial
carcinomas diagnosed in 2016. We assessed immunostaining and sequencing data and …

Purpose: Shallow whole-genome sequencing (sWGS) can detect copy-number (CN)
aberrations. In high-grade serous ovarian cancer (HGSOC) sWGS identified CN signatures …