Bleomycin loaded exosomes enhanced antitumor therapeutic efficacy and reduced toxicity
S Shaikh, M Younis, S Yingying, T Tanziela, L Yuan - Life Sciences, 2023 - Elsevier
Background Bleomycin (BLM) is a chemotherapeutic agent with potent antitumor activity
against the tumor. However, lung fibrosis is the main drawback that limits BLM use. Tumor …
against the tumor. However, lung fibrosis is the main drawback that limits BLM use. Tumor …
Immunomodulatory effect of PLGA-encapsulated mesenchymal stem cells-derived exosomes for the treatment of allergic rhinitis
KA Shahzad, Z Wang, X Li, J Li, M Xu… - Frontiers in …, 2024 - frontiersin.org
Introduction Allergic rhinitis (AR) is an upper airway inflammatory disease of the nasal
mucosa. Conventional treatments such as symptomatic pharmacotherapy and allergen …
mucosa. Conventional treatments such as symptomatic pharmacotherapy and allergen …
Amrubicin encapsulated PLGA NPs inhibits the PI3K/AKT signaling pathway by activating PTEN and inducing apoptosis in TMZ-resistant Glioma
M Younis, S Shaikh, KA Shahzad, F Tan… - Biomedical …, 2024 - iopscience.iop.org
Glioblastoma (GBM) remains a challenging malignancy due to its aggressive nature and the
lack of efficacious therapeutic interventions. Nanotechnology-based approaches exhibit …
lack of efficacious therapeutic interventions. Nanotechnology-based approaches exhibit …
Iguratimod prevents renal fibrosis in unilateral ureteral obstruction model mice by suppressing M2 macrophage infiltration and macrophage–myofibroblast transition
Y Zhou, Z Li, S Yu, X Wang, T Xie, W Zhang - Renal Failure, 2024 - Taylor & Francis
Iguratimod is a novel synthetic, small-molecule immunosuppressive agent used to treat
rheumatoid arthritis. Through ongoing exploration of its role and mechanisms of action …
rheumatoid arthritis. Through ongoing exploration of its role and mechanisms of action …
[HTML][HTML] Mebendazole induces apoptosis and inhibits migration via the reactive oxygen species-mediated STAT3 signaling downregulation in non-small cell lung …
Z Liang, Q Chen, L Pan, X She… - Journal of Thoracic …, 2024 - ncbi.nlm.nih.gov
Background The incidence and mortality of non-small cell lung cancer (NSCLC) are
extremely high. Previous research has confirmed that the signal transducer and activator of …
extremely high. Previous research has confirmed that the signal transducer and activator of …
Macrophage migration inhibitory factor as a therapeutic target in neuro-oncology: A review
Primary central nervous system (CNS) tumors affect tens of thousands of patients each year,
and there is a significant need for new treatments. Macrophage migration inhibitory factor …
and there is a significant need for new treatments. Macrophage migration inhibitory factor …
[PDF][PDF] 包载铑纳米颗粒的复合水凝胶对胰腺癌BxPC⁃ 3 细胞的杀伤效应
王宁薇， 张聪， 刘刚， 余跃 - 安徽医科大学学报, 2024 - aydxb.cn
摘要目的探究包载铑纳米颗粒的复合水凝胶NPN+ Rh⁃ PEG NPs (NRP) 对胰腺癌BxPC⁃ 3
细胞的杀伤效应. 方法首先利用原子转移自由基聚合(ATRP) 合成嵌段共聚物 …
细胞的杀伤效应. 方法首先利用原子转移自由基聚合(ATRP) 合成嵌段共聚物 …