Vasculitis of the medium and large arteries, most often presenting as giant cell arteritis
(GCA), is an infrequent, but potentially fatal, type of immune-mediated vascular disease. The …

Giant cell arteritis (GCA), also called Horton or granulomatous arteritis, is a large-and
medium-sized blood vessel systemic vasculitis characterized by the granulomatous …

Objective To compare the efficacy of abatacept to that of placebo for the treatment of giant
cell arteritis (GCA). Methods In this multicenter trial, patients with newly diagnosed or …

The objective of this study was to develop European League Against Rheumatism/American
College of Rheumatology classification criteria for polymyalgia rheumatica (PMR) …

Objective To provide a single source for the best available estimates of the US prevalence of
and number of individuals affected by osteoarthritis, polymyalgia rheumatica and giant cell …

Giant cell arteritis (GCA) is a granulomatous vasculitis affecting large arteries, especially the
aorta and the extracranial branches of the external carotid artery. Its exact pathogenesis is …

Background—In giant cell arteritis (GCA), vasculitic damage of the aorta and its branches is
combined with a syndrome of intense systemic inflammation. Therapeutically …

Objective To reevaluate the efficacy and safety of adjunctive low‐dose methotrexate (MTX)
in giant cell arteritis (GCA). Methods An individual patient data meta‐analysis of 3 …

In a search of new bone proteins, the glycoprotein YKL-40 was identified in 1989 to be
secreted in vitro in large amount by the human osteosarcoma cell line MG63. The protein …

Polymyalgia Rheumatica (PMR) presents with a broad spectrum of clinical manifestations
and almost exclusively occurs in the population aged over 50 years. After rheumatoid …