Acute kidney injury (AKI) is a common and serious problem affecting millions and causing
death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes …

Background COVID-19-associated acute respiratory distress syndrome (ARDS) is
associated with significant morbidity and high levels of mortality. This paper describes the …

In experimental studies, the old mucolytic agent N‐acetylcysteine (NAC) has had beneficial
effects in disorders supposedly linked to oxidative stress. Numerous, mainly small clinical …

Background Death is common in systemic inflammatory response syndrome (SIRS) or
sepsis‐induced multisystem organ failure and it has been thought that antioxidants such as …

Oxidative stress and inflammation generate edema in burns. The aim of our study was to
assess effect of N-acetylcysteine (NAC) on oxidative stress, inflammation, fluid requirement …

Perioperative acute renal failure (ARF) is associated with increased morbidity and mortality.
Patients undergoing cardiac, vascular and major abdominal surgery and those with pre …

The pathogenesis of sepsis-induced acute kidney injury (AKI) is not fully understood, and
may involve altered systemic hemodynamics and renal circulation, renal hypoxia and …

BACKGROUND: Acute renal failure after major surgery is associated with significant
mortality and morbidity that theoretically may be attenuated by N-acetylcysteine. DESIGN …

SummaryBackground and objective: The use of a pneumatic tourniquet can induce
muscular and neurological complications in the operated limb. The genesis of these injuries …

Glutathione (GSH) deficiency may play a pivotal role in a variety of apparently unrelated
clinical conditions and diseases. Orally administered N-acetylcysteine (NAC), which …