Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging

YXJ Wang, SM Hussain, GP Krestin - European radiology, 2001 - Springer
Superparamagnetic iron oxide MR imaging contrast agents have been the subjects of
extensive research over the past decade. The iron oxide particle size of these contrast …

Iron oxide MR contrast agents for molecular and cellular imaging

JWM Bulte, DL Kraitchman - NMR in Biomedicine: An …, 2004 - Wiley Online Library
Molecular and cellular MR imaging is a rapidly growing field that aims to visualize targeted
macromolecules or cells in living organisms. In order to provide a different signal intensity of …

Visual motion processing investigated using contrast agent-enhanced fMRI in awake behaving monkeys

W Vanduffel, D Fize, JB Mandeville, K Nelissen… - Neuron, 2001 - cell.com
To reduce the information gap between human neuroimaging and macaque physiology and
anatomy, we mapped fMRI signals produced by moving and stationary stimuli (random dots …

Evidence of a cerebrovascular postarteriole windkessel with delayed compliance

JB Mandeville, JJA Marota, C Ayata… - Journal of Cerebral …, 1999 - journals.sagepub.com
A pronounced temporal mismatch was observed between the responses of relative cerebral
blood volume (rCBV) measured by magnetic resonance imaging and relative cerebral blood …

Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation

JB Mandeville, JJA Marota, BE Kosofsky… - Magnetic resonance …, 1998 - Wiley Online Library
Dynamic measurements of regional changes in cerebral blood volume (CBV) were
performed in rat models of hypercarbia and focal neuronal activation using T2‐weighted …

Characterization and MRI study of surfactant-coated superparamagnetic nanoparticles administered into the rat brain

DK Kim, Y Zhang, J Kehr, T Klason, B Bjelke… - Journal of Magnetism …, 2001 - Elsevier
A pre-clinical study has been carried out for the utilization of magnetite (Fe3O4)
nanoparticles as a diagnostic tracer for MRI. Surfactant-coated Fe3O4 nanoparticles have …

Magnetically labeled cells can be detected by MR imaging

R Weissleder, HC Cheng, A Bogdanova… - Journal of Magnetic …, 1997 - Wiley Online Library
To determine the feasibility of MR imaging of magnetically labeled cells, different cell lines
were labeled with monocrystalline iron oxide (MION) particles. Phantoms containing MION …

Tissue-specific MR contrast agents

HJ Weinmann, W Ebert, B Misselwitz… - European journal of …, 2003 - Elsevier
The purpose of this review is to outline recent trends in contrast agent development for
magnetic resonance imaging. Up to now, small molecular weight gadolinium chelates are …

Magnetic resonance imaging contrast agents: overview and perspectives

GP Yan, L Robinson, P Hogg - Radiography, 2007 - Elsevier
Magnetic resonance imaging (MRI) is a non-invasive clinical imaging modality, which has
become widely used in the diagnosis and/or staging of human diseases around the world …

Targeting of ultrasmall superparamagnetic iron oxide (USPIO) particles to tumor cells in Vivo by using transferrin receptor pathways

M Kresse, S Wagner, D Pfefferer… - Magnetic …, 1998 - Wiley Online Library
Human transferrin was covalently coupled to ultrasmall superparamagnetic iron oxide
(USPIO) particles, and the trans‐ferrin‐USPIO obtained was investigated in vivo in …