[HTML][HTML] Vaccination in the elderly: the challenge of immune changes with aging
The unprecedented increase of life expectancy challenges society to protect the elderly from
morbidity and mortality making vaccination a crucial mean to safeguard this population …
morbidity and mortality making vaccination a crucial mean to safeguard this population …
Updates on immunologic correlates of vaccine-induced protection
SA Plotkin - Vaccine, 2020 - Elsevier
Correlates of protection (CoPs) are increasingly important in the development and licensure
of vaccines. Although the study of CoPs was initially directed at identifying a single immune …
of vaccines. Although the study of CoPs was initially directed at identifying a single immune …
Recent updates on correlates of vaccine-induced protection
SA Plotkin - Frontiers in Immunology, 2023 - frontiersin.org
Correlates of protection are key for vaccine development against any pathogen. In this paper
we summarize recent information about correlates for vaccines against dengue, Ebola …
we summarize recent information about correlates for vaccines against dengue, Ebola …
A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge
Background Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public
health as demonstrated by its high associated mortality rate (23–90%) and recent …
health as demonstrated by its high associated mortality rate (23–90%) and recent …
Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population
The SARS-CoV-2 pandemic urgently calls for the development of effective preventive tools.
COVID-19 hits greatly the elder and more fragile fraction of the population boosting the …
COVID-19 hits greatly the elder and more fragile fraction of the population boosting the …
Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates
Summary The 2013 Ebola epidemic in Central and West Africa heralded the emergence of
wide-spread, highly pathogenic viruses. The successful recombinant vector vaccine against …
wide-spread, highly pathogenic viruses. The successful recombinant vector vaccine against …
Advances in vaccines
HH Mao, S Chao - Current Applications of Pharmaceutical Biotechnology, 2020 - Springer
Vaccines represent one of the most important advances in science and medicine, helping
people around the world in preventing the spread of infectious diseases. However, there are …
people around the world in preventing the spread of infectious diseases. However, there are …
Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26. ZEBOV/MVA-BN-Filo
F Blengio, H Hocini, L Richert, C Lefebvre, M Durand… - Cell Reports, 2023 - cell.com
Ebola virus disease is a severe hemorrhagic fever with a high fatality rate. We investigate
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …
Inhibition of Ebola virus by a molecularly engineered banana lectin
EM Covés-Datson, J Dyall, LE DeWald… - PLoS neglected …, 2019 - journals.plos.org
Ebolaviruses cause an often rapidly fatal syndrome known as Ebola virus disease (EVD),
with average case fatality rates of~ 50%. There is no licensed vaccine or treatment for EVD …
with average case fatality rates of~ 50%. There is no licensed vaccine or treatment for EVD …
Predicting the combined effects of case isolation, safe funeral practices, and contact tracing during Ebola virus disease outbreaks
A Bouba, KB Helle, KA Schneider - PloS one, 2023 - journals.plos.org
Background The recent outbreaks of Ebola virus disease (EVD) in Uganda and the Marburg
virus disease (MVD) in Ghana reflect a persisting threat of Filoviridae to the global health …
virus disease (MVD) in Ghana reflect a persisting threat of Filoviridae to the global health …