Nitrogenase is the enzyme that catalyzes biological N2 reduction to NH3. This enzyme
achieves an impressive rate enhancement over the uncatalyzed reaction. Given the high …

The reduction of dinitrogen to ammonia by nitrogenase reflects a complex choreography
involving two component proteins, MgATP and reductant. At center stage of this process …

Nitrogenase is the only enzyme capable of reducing N2 to NH3. This challenging reaction
requires the coordinated transfer of multiple electrons from the reductase, Fe-protein, to the …

Nitrogenase harbors three distinct metal prosthetic groups that are required for its activity.
The simplest one is a [4Fe-4S] cluster located at the Fe protein nitrogenase component. The …

Nitrogenases are responsible for biological nitrogen fixation, a crucial step in the
biogeochemical nitrogen cycle. These enzymes utilize a two-component protein system and …

The enzyme nitrogenase couples adenosine triphosphate (ATP) hydrolysis to the
multielectron reduction of atmospheric dinitrogen into ammonia. Despite extensive research …

Nitrogenases are best known for catalyzing the reduction of dinitrogen to ammonia at a
complex metallic cofactor. Recently, nitrogenases were shown to reduce carbon dioxide …

Conspectus The fixation of atmospheric dinitrogen to ammonia by industrial technologies
(such as the Haber Bosch process) has revolutionized humankind. In contrast to industrial …

The ubiquity, structural variation, and functional diversity of iron-sulfur (Fe-S) clusters in
biological environments has long fascinated scientists. In nature, Fe-S clusters form a variety …

Ammonia is crucial for the fertilizer industry and the global chemical economy. However, the
conventional Haber–Bosch process for NH3 synthesis is energy and capital-intensive and …