Functional Annotation of Animal Genomes (FAANG): current achievements and roadmap
Functional annotation of genomes is a prerequisite for contemporary basic and applied
genomic research, yet farmed animal genomics is deficient in such annotation. To address …
genomic research, yet farmed animal genomics is deficient in such annotation. To address …
Challenges and opportunities in genetic improvement of local livestock breeds
Sufficient genetic variation in livestock populations is necessary both for adaptation to future
changes in climate and consumer demand, and for continual genetic improvement of …
changes in climate and consumer demand, and for continual genetic improvement of …
Integrating crop growth models with whole genome prediction through approximate Bayesian computation
Genomic selection, enabled by whole genome prediction (WGP) methods, is revolutionizing
plant breeding. Existing WGP methods have been shown to deliver accurate predictions in …
plant breeding. Existing WGP methods have been shown to deliver accurate predictions in …
Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits
Many genome variants shaping mammalian phenotype are hypothesized to regulate gene
transcription and/or to be under selection. However, most of the evidence to support this …
transcription and/or to be under selection. However, most of the evidence to support this …
Model training across multiple breeding cycles significantly improves genomic prediction accuracy in rye (Secale cereale L.)
HJ Auinger, M Schönleben, C Lehermeier… - Theoretical and applied …, 2016 - Springer
Key message Genomic prediction accuracy can be significantly increased by model
calibration across multiple breeding cycles as long as selection cycles are connected by …
calibration across multiple breeding cycles as long as selection cycles are connected by …
Genomic prediction using a reference population of multiple pure breeds and admixed individuals
Background In dairy cattle populations in which crossbreeding has been used, animals
show some level of diversity in their origins. In rotational crossbreeding, for instance …
show some level of diversity in their origins. In rotational crossbreeding, for instance …
Integrating sequence-based GWAS and RNA-Seq provides novel insights into the genetic basis of mastitis and milk production in dairy cattle
Connecting genome-wide association study (GWAS) to biological mechanisms underlying
complex traits is a major challenge. Mastitis resistance and milk production are complex …
complex traits is a major challenge. Mastitis resistance and milk production are complex …
SNPchiMp v. 3: integrating and standardizing single nucleotide polymorphism data for livestock species
Background In recent years, the use of genomic information in livestock species for genetic
improvement, association studies and many other fields has become routine. In order to …
improvement, association studies and many other fields has become routine. In order to …
Using sequence variants in linkage disequilibrium with causative mutations to improve across-breed prediction in dairy cattle: a simulation study
I van den Berg, D Boichard… - G3: Genes …, 2016 - academic.oup.com
Sequence data are expected to increase the reliability of genomic prediction by containing
causative mutations directly, especially in cases where low linkage disequilibrium between …
causative mutations directly, especially in cases where low linkage disequilibrium between …
Sequence variants selected from a multi-breed GWAS can improve the reliability of genomic predictions in dairy cattle
I Van den Berg, D Boichard, MS Lund - Genetics Selection Evolution, 2016 - Springer
Background Sequence data can potentially increase the reliability of genomic predictions,
because such data include causative mutations instead of relying on linkage disequilibrium …
because such data include causative mutations instead of relying on linkage disequilibrium …