Neuropsychiatric lupus: new mechanistic insights and future treatment directions

N Schwartz, AD Stock, C Putterman - Nature Reviews Rheumatology, 2019 - nature.com
Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

[HTML][HTML] Neuropsychiatric systemic lupus erythematosus: a 2021 update on diagnosis, management, and current challenges

S Sarwar, AS Mohamed, S Rogers, ST Sarmast… - Cureus, 2021 - ncbi.nlm.nih.gov
Patients with systemic lupus erythematosus (SLE) experience neuropsychiatric symptoms.
The term neuropsychiatric SLE (NPSLE) is a generic term that refers to a series of …

[HTML][HTML] Machine learning application in autoimmune diseases: State of art and future prospectives

MG Danieli, S Brunetto, L Gammeri, D Palmeri… - Autoimmunity …, 2024 - Elsevier
Autoimmune diseases are a group of disorders resulting from an alteration of immune
tolerance, characterized by the formation of autoantibodies and the consequent …

Neuropsychiatric involvement in systemic lupus erythematosus: a review

I Carrión-Barberà, TC Salman-Monte, F Vílchez-Oya… - Autoimmunity …, 2021 - Elsevier
The neuropsychiatric involvement in systemic lupus erythematosus (NPSLE) is a challenge
for clinicians, both at a diagnostic and therapeutic level. Although in 1999 the American …

The management of neuropsychiatric lupus in the 21st century: still so many unmet needs?

M Govoni, JG Hanly - Rheumatology, 2020 - academic.oup.com
Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Lupus vasculitis: an overview

P Leone, M Prete, E Malerba, A Bray, N Susca… - Biomedicines, 2021 - mdpi.com
Lupus vasculitis (LV) is one of the secondary vasculitides occurring in the setting of systemic
lupus erythematosus (SLE) in approximately 50% of patients. It is most commonly …

Central nervous system systemic lupus erythematosus: pathophysiologic, clinical, and imaging features

Y Ota, A Srinivasan, AA Capizzano, JR Bapuraj… - Radiographics, 2022 - pubs.rsna.org
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by
multiple immunologic abnormalities and has the potential to involve the central nervous …

Brain-reactive autoantibodies in neuropsychiatric systemic lupus erythematosus

C Cocco, E Manca, G Corda, MM Angioni… - Frontiers in …, 2023 - frontiersin.org
Introduction The pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) is
widely unknown, and the role of autoantibodies is still undetermined. Methods To identify …

Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus

M Gueye, P Preziosa, GA Ramirez, EP Bozzolo… - Molecular …, 2024 - nature.com
Choroid plexus (CP) enlargement is proposed as a marker of neuroinflammation in immune-
mediated conditions. CP involvement has also been hypothesized in the immunopathology …

Stroke in systemic lupus erythematosus and antiphospholipid syndrome: risk factors, clinical manifestations, neuroimaging, and treatment

LCD De Amorim, FM Maia, CEM Rodrigues - Lupus, 2017 - journals.sagepub.com
Neurologic disorders are among the most common and important clinical manifestations
associated with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) …