Many drugs, or their antecedents, were discovered through observation of their effects on
normal or disease physiology. For the past generation, this phenotypic drug discovery …

Abstract Microplastics (MPs) and nanoplastics (NPs) have received global concern due to its
widespread contamination, ingestion in aquatic organisms and the ability to cross the …

Animal models are essential tools for addressing fundamental scientific questions about
skeletal diseases and for the development of new therapeutic approaches. Traditionally …

The zebrafish is ideal for studying embryogenesis and is increasingly applied to model
human disease. In these contexts, RNA-sequencing (RNA-seq) provides mechanistic …

Deltamethrin is responsible for health and reproduction problems both in mammals and
aquatic organisms. In this study, zebrafish adults were exposed for 15 days to 0.25, 0.5, 1 …

Zebrafish exhibit robust regeneration following spinal cord injury, promoted by macrophages
that control post-injury inflammation. However, the mechanistic basis of how macrophages …

We have prepared a series of ten 3-arylcoumarin molecules, their respective fac-[Re (CO) 3
(bpy) L]+ and fac-[Re (CO) 3 (L⁀ L) Br] complexes and tested all compounds for their …

The increasing number of available anti-cancer drugs presents a challenge for oncologists,
who must choose the most effective treatment for the patient. Precision cancer medicine …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that leads to
progressive disability and motor impairment. Existing therapies provide modest …

In this review, we discuss the possible utility of zebrafish in research on psilocybin, a
psychedelic drug whose recreational use as well as possible clinical application are gaining …